The effectiveness of using «Asepta plus remineralization» special toothpaste, combination of the same toothpaste and «Asepta parodontal fresh» rinse or «Asepta remineralizing gel» (Vertex CJSC, St. Petersburg, Russia) using analysis technique of the structure and severity of the interior disease sight based on psychosensorial-anatomy-functional desadaptation syndrome. It was established that patients who used «Asepta plus remineralization» toothpaste and «Asepta remineralizing gel» on day 3 showed adaptation to the conditions of their existence. Among the patients using «Asepta plus remineralization» toothpaste and «Asepta parodontal fresh» rinse, despite the positive clinical effect of their use on day 3, there was a violation of adaptability to living conditions. In case of the isolated using of «Asepta plus remineralization» toothpaste for oral hygiene, adaptation to their conditions of existence occurred by 7 days of patient observation. The obtained information is important for planning secondary prevention events for dental hyperesthesia, which allows recommending oral care products to patients taking into account the peculiarities of the clinical course of this pathology. 

This article reflects clinical studies on the cause of xerostomy in children with systemic connective tissue disease (CTS). For more than 20 years, we have provided comprehensive dental care to children with CTS and have found that the presence of xerostomy and destructive changes in the parotid salivary glands in children with CTS, are characteristic of the manifestation of Shegren syndrome and contributed to: development of multiple tooth decay in the cervical area, the presence of abundant plaque on the teeth, inflammatory diseases of the gums and mucous membranes of the mouth and lips, the joining of secondary infection. 

Relevance. According to modern concepts, virulent representatives of periodontal pathogenic bacteria are actively involved in the development of both periodontal pathology and various forms of odontogenic infection. The species diversity of these pathogens determines the need for a combined approach when choosing antimicrobial drugs.

The aim of the work is to provide a microbiological substantiation of the use of a combined dosage form of ciprofloxacin and tinidazole for the treatment of periodontal and odontogenic infections based on the determination of the spectrum of action and the characteristics of the activity of the components.

Materials and methods. Determination of the sensitivity of various strains of periodontal and odontogenic infection pathogens (P. intermedia, S. constellatus; S. sanguis, K. pneumoniae, S. aureus – MRSA) was carried out by the method of automated cultivation of strains with different concentrations of the tested drugs – ciprofloxacin and tinidazole.

Results. Differences in the activity of the components of the combined preparation ciprofloxacin and tinidazole were found in terms of the sensitivity of strains of aerobic and anaerobic pathogens to them. Aerobic strains, including MRSA, were inhibited by ciprofloxacin in a low concentration range (6.25 μg / ml), but for some anaerobic strains the activity of ciprofloxacin was borderline (12.5 μg / ml). This confirmed the need to include tinidazole in the composition of the complex preparation.

Conclusion. The combination of ciprofloxacin and tinidazole provides coverage of the full spectrum of periodontal and odontogenic infections and can be used as the agent of choice in the antimicrobial chemotherapy algorithm for head and neck infections. 

The purpose of this review article is to analyze the current data on the use of antiseptics in the treatment of periodontitis, development of resistance of periodontopathogens to antiseptic agents using the example of chlorhexidine, cetylpyridinium chloride and hexetidine. Periodontal pathogens are an integral part of the commensal microflora of the oral cavity, but under certain conditions and under the influence of etiological factors, their number begins to progressively grow, which increases the risk of initiation of periodontal diseases through the formation of aggressive biofilm on the teeth.

Materials and methods. Тhe study of publications was produced in the electronic databases such as PubMed and Google Scholar in the course of a systematic review of the literature. Included articles contain information about antiseptic agents which are chlorhexidine, cetylpyridinium chloride and hexetidine, as well as their effect on periodontopathogens and the possibility of developing resistance in them against these antiseptics.

Results. 127 articles were viewed during the review. After analyzing the literature for inclusion criteria, the total number of publications has become 94.

Conclusions. Аccording to the analyzed data, we have found that antiseptic treatment of the oral cavity and lesions in periodontitis is an integral part of the treatment of this inflammatory disease, as an addition to the mechanical treatment protocol. Chlorhexidine in local forms of delivery has shown particular activity against periodontopathogens. 

The issues of structural organization, function and diagnosis of diseases of the temporomandibular joint have long attracted the attention of not only morphologists, dentists, maxillofacial surgeons, but also doctors of related specialties. Temporomandibular disorders are among the most common non-odontogenic pain syndromes in the maxillofacial region and are considered a variant of musculoskeletal pain syndrome. Based on the analysis of the results of clinical and functional studies, an algorithm for the management of patients with terminal dentition defects complicated by signs of painful dysfunction of the temporomandibular joint was proposed. Therapeutic measures, depending on the degree of painful dysfunction of the temporomandibular joint, included the following stages: occlusive splint therapy; physiotherapy treatment with dynamic electroneurostimulation; prosthetic treatment of end defects of the dentition; stabilization of the spatial relationship of the jaws. Complex therapeutic measures are aimed at normalizing the functional activity of the dentoalveolar apparatus by restoring the uniform distribution of the occlusal load. 

Various types of techniques increase the volume of the atrophied alveolar ridge are used as bone blocks, ridge splitting, osteoperiostal flap, etc. However, one of the most promising methods to date is the GBR method. The use of bone-substituting materials and isolating membranes gives a reliable and predictable result in dental implantology. Recent studies using the dPTFE (dense polytetrafluoroethylene ) membrane have shown a positive result at the site of regeneration even if the membrane itself is exposed in repaired period. With this type of complication the membrane is removed at a period of 4–6 weeks and replaced with a collagen membrane with subsequent approximation of the edges of the flap by sutures (24, 25). This article shows the possibility of regenerating the bone graft from sole xenogenic material using dPTFE membrane in case wound dehiscence in repaired period but without using the collagen membrane coating step after removing dPTFE and it healing by secondary tension. 

Dens evaginatus (DE) is an odontogenic developmental abnormality that can be defined as a tubercle or bulge on the surface of a tooth, consisting of the outer layer of enamel, dentin, and possibly pulp. Early diagnosis and treatment of dental evagination is important to prevent untimely endodontic treatment, occlusal trauma, aesthetics, and the development of fissure caries. This pathology of tooth development is usually found on the premolars of the lower jaw as an additional tubercle or bulge between the buccal and lingual tubercles. DE in the maxillary premolar has been reported rarely in the literature. We report one such rare case in the maxillary premolar.

Material and methods. The article describes a clinical case of treating a patient with dental evagination. For observation, we used X-ray images made with CBCT, as well as a photo protocol of the stages of patient treatment.

Conclusions. Since this pathology is rare, the description of this clinical case will help doctors better understand the approaches to dental treatment with such anomalies in the development of tooth tissues. 

Based on the results of morphological studies of the craniofacial complex, biometrics of plaster models of the jaws of 76 young people (18-25 years old) with asymmetry of dental arches, an algorithm was developed for modeling the predicted sizes of dental arches with their asymmetry in the diagonal direction. The methodological approach is based on the use of individual cephalometric indicators (diagonal and transverse face size), morphometric parameters of dental arches (incisor-molar diagonal, transverse intermolar arch size, dental arch depth) and stable correction factors for assessing the conformity (inconsistency) of real and predicted biometric data. Further stages of modeling the predicted sizes of dental arches with their asymmetry in the diagonal direction include the construction of incisor-molar and incisor-canine triangles, taking into account the anthropometric parameters of the maxillofacial region. The use of a diagnostically significant method in the clinic of orthodontics makes it possible to establish the topography of key teeth (canines, second molars) in the dental arch, taking into account the individual characteristics of the patient’s craniofacial complex. The implementation of the obtained results in clinical dentistry in patients with asymmetry of dental arches in the diagonal direction is advisable to substantiate the methods (extraction, without extraction) of complex treatment in order to achieve a functional balance of occlusal relationships, as well as optimal balance of morphological, functional and aesthetic characteristics. 

This article reflects clinical trials, follow-up and the results of dental care for more than 20 years to children with juvenile scleroderma (JSD). We developed an algorithm for providing dental care to children with JSD, which consisted of successive stages: elimination of acute inflammatory phenomena in the maxillofacial area; elimination of chronic odontogenous pockets; oral sanitization; local anti-fibrin, anti-sclerotic therapy and preventive measures. The principles developed and used by us dental care for children with JSD according to our observations significantly reduced the risk of exacerbation of the underlying disease and the joining of secondary infection. 

Ultrasound is able to have a multifaceted therapeutic effect in periodontitis. In therapeutic doses, it affects a variety of local tissue reactions, stimulates compensatory, restorative, protective and adaptive mechanisms.

Ultrasound in dosages used in clinical practice does not have an independent, direct antibacterial effect. In this regard, in the treatment of periodontitis, where the microbial factor plays an important role, it is advisable to use antiseptic solutions as a contact medium for ultrasonic effects. The study of the comparative effectiveness of low-frequency and high-frequency ultrasonic effects in combination with the domestic antiseptic preparation miramistin, which, with high antibacterial effectiveness, is characterized by the absence of adverse side effects, in the treatment of periodontitis, is of significant scientific and practical importance. 

The article discusses the issues of diagnosis and treatment of malignant tumors of the maxillofacial region on the example of a rare clinical case of aggressive malignant neoplasm of the upper jaw. 

At the dental reception, complications after dental implantation in the form of mucositis and peri-implantitis are becoming more and more common. There are quite a lot of risk factors for the development of inflammation of the parotid tissue, there is no single idea about the etiopathogenesis of the above pathology. Mucositis refers to the initial stage of peri-implantitis development and is reversible. The specialist should promptly diagnose the development of the inflammatory potential and start treatment, in order to prevent the development of bone destruction around the implants. One of the methods of local exposure to the lesion is ozone therapy.

Goal. This paper describes the method of treatment of peri-implantation mucositis by ozone therapy.

Materials and methods. In patients with peri-implantation mucositis, the inflammatory peri-implantation tissue was ozonated directly in the oral cavity with the Ozotron device in order to relieve inflammation and improve microcirculation in the oral cavity. Before performing oral ozonation, all patients underwent a general clinical examination to identify contraindications to this method. It also describes in detail the scheme that prevents the penetration of ozone into the body and prevents its ingestion.

Results. During ozonation, a positive trend was obtained in the treatment of post-prosthetic complications during dental implantation. The developed scheme of ozonation in the oral cavity stops the inflammation of the peri-implantation tissue. Side effects and complications during ozone therapy directly in the oral cavity were not detected.

Conclusions. The inclusion of ozone therapy in the treatment regimen of patients with peri-implantation mucositis is an appropriate and justified physiotherapy method.