Leukoplakia is keratinization of the oral mucosa or the red border of the lips, which occurs in response to chronic exogenous irritation, and refers to a facultative precancer with a probability of malignant transformation up to 9.5%. The greatest danger is verrucous and erosive-ulcerative form of oral leukoplakia.

Our accumulated clinical experience has shown the effectiveness of laser ablation for excision of problem areas in oral leukoplakia. In the postoperative period, a good result was obtained when using a collagen-based drug. The clinical case of laser ablation and collagen-based drug shown in the article showed a good clinical result, which makes it possible to optimize dental care for this group of patients.

In the modern implantology, it is difficult to imagine a comprehensive prosthodontics rehabilitation without the use of dental implants. Installing implants in a simple case does not cause much difficulty. However, at conditions of bone deficit, it is necessary to expand the scope of implantology planning and treatment: digital and computer modeling, navigation surgery, simultaneous of implantation with various methods of bone augmentation. As the implantation procedure becomes more complex, the risk of treatment complications increases.

Purpose: to reveal the dependence of the degree of atrophic processes in the supporting tissues of the prosthetic bed in patients using various types of removable dentures on the length and topography of the dentition defect and the time of using the prosthesis.

Materials and methods. A survey of 50 patients who applied to the clinic of orthopedic dentistry for the purpose of repeated prosthetics at the age of 40 to 65 years was carried out.

Results. There were revealed statistically significant changes in the tissues of the prosthetic bed when using removable dentures from 12 to 24 months, from 0.35 ± 0.1 to 0.8 ± 0.1 mm. Moreover, with the included defects of short length under the plate prostheses, the change in the relief of the prosthetic bed was 0.61 ± 0.1 mm, while under the clasp prostheses - 0.37 ± 0.1 mm. When assessing changes in the relief of supporting tissues with defects of great length after 24 months, atrophy increased from 2 to 3 times, and amounted to 1.83 ± 0.1 mm under plate prostheses, and 0.74 ± 0.1 mm under clasp prostheses, respectively.

Conclusion. The processes of atrophy of the supporting tissues of the prosthetic bed in patients using plate designs of removable dentures are more pronounced with extended terminal defects of the dentition starting from 12 months and up to 24 months, and the smallest changes were observed in patients using clasp prostheses in the first 6 months.

During the experiment, three artificial defects were created on the outer surface of the jaw body of experimental animals. Two wells were filled with bone substitute materials, one well was not filled with anything and remained as a control. The defects formed and filled with materials were closed with titanium membranes with different through porosity. in order to study the effect of titanium membranes with varying degrees of porosity on osteoreparative processes in the area of defects, histological studies were carried out. As a result, it was determined that bone recovery was the same both in the group where titanium membranes with a pore diameter of 0.25 mm were used and in the group where titanium membranes with a pore diameter of 1.0 mm were used.

In order to determine the possibility of using computer technologies in the analysis of the dentoalveolar arches parameters, a retrospective analysis of 146 computer tomograms was carried out. The results obtained are consistent with the literature data that it is impossible to obtain accurate data on its parameters from the image of the dental and basal arches on a computed tomogram.

The aim of this study was to analyze and systematize the assessment of the TMJ MRI results of the patients with TMJ diseases in order to improve treatment and prevention methods. The study was carried out in T-1, T-2 weighted images with processing in the interfaces of programs Syngo FV Siemens Medical Solutions and Picasso Viewer and others. Having studied modern methods of diagnosis and treatment of patients with TMJ dysfunctions, we came to the conclusion that the most informative method of morphological analysis and the functional state of TMJ is an MRI diagnosis. The morphofunctional disturbances of the TMJ revealed at the early stages of the pathology formation allow timely implementation of preventive measures and reduce the number of patients requiring invasive treatment methods. The results of the analysis of MRI of the TMJ made it possible to plan the prevention or treatment of patients with TMJ dysfunctions, depending on the revealed violations of the TMJ elements.

The increase in the incidence of type 1 diabetes mellitus in the child population over the past decades and the lack of adequate control of the disease dictate the advisability of a comprehensive study of the quality of life of this category of patients. Assessment of the quality of life complements a comprehensive medical examination and allows the most complete assessment of the child’s health, to develop rational approaches to therapy and rehabilitation. The quality of life was studied in 119 adolescents with type 1 diabetes mellitus and the duration of the disease from one to twelve years. The control group consisted of 83 practically healthy adolescents, matched by sex and age. We used the PedsQL 4.0 Pediatric Quality of Life Questionnaire for children aged 13 to 18 years: general (Generic Core Scales) and special (Diabetes Module) modules. For non-drug correction of microvascular disorders in the periodontium, in addition to traditional treatment (basal-bolus insulin therapy and symptomatic therapy), magnetic laser therapy and enzyme therapy were prescribed. it was found that the self-assessment of the quality of life of healthy children, as well as those with type 1 diabetes mellitus, exceeds the indicators of the parents’ assessment. When assessing the quality of life in adolescents with type 1 diabetes mellitus, the achievement of target glycemic indicators was noted, which is associated with control by parents, as well as self-discipline and personal manifestations of responsibility? The effectiveness of the proposed schemes of pharmaco-physiotherapeutic action in combination with basic-bolus insulin therapy and symptomatic therapy in children with different experience with type 1 diabetes mellitus has been proven by consistently stable quality of life indicators, especially in the scales «Problems associated with treatment 1» and «Problems associated with treatment 2,».

The article discusses the most common causes of maxillary sinus perforation and odontogenic perforated sinusitis in modern conditions. Perforation of the bottom of the cavity of the maxillary sinus is one of the most common complications arising directly during the operation of tooth extraction. The resulting communication between the oral cavity and the nasal cavity should be eliminated as soon as possible in the most optimal way. Rational diagnostics, treatment and methods of prophylactic activities of mentioned above complications were also suggested.

The purpose of this study was to carry out a comparative assessment of two types of bone substitute materials for targeted bone regeneration, on a mineral basis and on the basis of collagen. During the experiment, artificial defects were created on the outer surface of the jaw body of experimental animals. Two defects were replaced with osteoplastic materials with different degrees of mineralization, one defect remained under the clot. Histological examinations of biopsy specimens were performed. It was revealed that when using demineralized bone substitute materials, the processes of bone tissue repair occur more intensively.