In the complex treatment of patients with tuberculosis with destruction of pulmonary tissue in the presence of drug-resistant pathogen in 10.2 % of cases it is necessary to resort to surgery in the form of resection or pulmonectomy. In the postoperative period, there are cases of progression of a specific process in the lungs with the formation of destruction. In such a situation, the optimal choice of treatment strategy is endoscopic valve bronchomalacia (ECB) with maximum preservation of functioning lung tissue. The aim of this work is to study the dynamics of ventilation and gas exchange function of the lungs in patients with acute pulmonary tissue destruction after surgery. The study revealed a change in the functional state of the lungs in 56 % of cases: negative in 39 % of patients and positive — in 17 %. The nature of the changes associated with the initial state of the bronchopulmonary apparatus and the characteristics of drug resistant. Deterioration of function is more often observed in a two-sided process and/or in the presence of two or more caverns. The initial state of the lung ventilation capacity and the presence of signs of restrictive disorders have the opposite effect on the functional outcome of bronchoblocation: at normal values of FEV1 and ESRD IS accompanied by more frequent broncho-obstructive disorders and deterioration of gas exchange rates than at their reduced values. The same paradoxical functional dependence of the dynamics can be traced in the volume «off» when drug resistant and its effectiveness.

A unique feature of electroencephalography (EEG) in patients with primary and secondary brain damage, accompanied by impaired consciousness, is the possibility of reducing the number of recording electrodes and the high frequency of occurrence of stereotypical combinations of graphoelements (special patterns). In EEG reporting in these patients, it is possible to use the special classification developed in 2013, which designates them as “rhythmic and periodic patterns” (RPP). Its implementation significantly increases the degree of inter-rater agreement, and clinical use allows not only to diagnose non-convulsive epileptic status accurately but to predict its occurrence at the preclinical stage and to assess the likelihood of recovery of consciousness in patients with coma. The review outlines the features of EEG recording in unconsciousness patients and describes the reporting methodology of rhythmic and periodic EEG patterns.

The pilot results of the contrast — enhanced ultrasound (CEUS) application in the liver parenchyma assessment are presented in this article. 65 people aged 37 to 69 years were examined, 41 of them (63 %) with chronic viral hepatitis and 24 people (37 %) with established diagnosis of liver cirrhosis as the outcome of viral hepatitis. All patients underwent multiparametric ultrasound examination: ultrasound of the liver in B — mode, color Doppler’s mapping of liver vessels, 2D — Shear Wave Elastography (2DSWE) and CEUS. Liver biopsy and D — Shear Wave Elastography (2DSWE) were used as the reference method.

This research is organized to investigate if the thermal gradient (T_grad) (difference between temperature maximum and minimum in the region of interest over thyroid gland on neck thermogramm) could be a marker of normal/ abnormal thyroid function and, if so, find out the cut-off value and check it screening validity.

Materials and methods. Thermography examination was performed using a TVS-300 med (S-Petersburg, Russia) thermal imaging camera with a resolution of 384 × 288 pixels and sensitivity was <0.04 °C according to European Association of Thermology standards. Anterior neck thermografic images were performed and collected in cloud database, where, by mean of program tools, region of interest were marked and T_grad calculated. Totally 1025 pts with different thyroid pathology (group 1: female 944, age 15–90 (55,4±15,8), male 81, age 14–86 (53,6±18,8)), and 395 healthy persons (group 2: male 324 age 17–26 (21,8±4,4), female 71 age 16–70т (34,6±12,7)) were investigated. To check the quality of the model another 314 persons (18 male and 296 female) were studied in screening mode.

Results. Calculated T_grad value was 1,65±0,53 °C, Ме 1,53(1,24; 1,90) and 0,98±0,23 °C, Me 1,01(0,82; 1,15) for group 1 and 2 accordingly. By mean of binary logistic regression analysis we found good correlation between T_grad value and presence/absence of thyroid pathology: significance level р<0,0001, χ² = 838,84, df = 1, β 0 = 9,984, β 1 = –9,033. Area under curve in ROC analysis was 0,922 (95 % CI 0,908; 0,935), р<0,001; optimal cut off value for T_grad was 1,21 °C for maximal sensitivity (79,8 %) and specificity (83,3 %). In screening evaluation, according to optimal cut-off value 1,2 °C for T_grad , 82,2 % of cases were classified correctly: true-positive and true-negative results were achieved in 258 from 314 pts.

Conclusion. Thermography test, based on T_grad value calculation, could help to distinguish persons with normal and abnormal function of thyroid gland.

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of mortality in the world. Exacerbations of COPD is considered an independent risk factor for pulmonary embolism (PE). PE is also significant problem of modern medicine, because mortality in PE remains at a high level. Exacerbations of COPD are heterogeneous as by etiology as by phenotype of the inflammatory response. It is presents the clinical case of PE in patient with acute exacerbation of COPD with eosinophilic phenotype of inflammation. It was the presence of a floating venous thrombus in the patient, which could become a source of repeated PE at any time. The patient underwent endovascular intervention — thrombus fragmentation and thromboaspiration. Given the signs of eosinophilic inflammation, systemic glucocorticosteroids have also been prescribed. The result of the intervention was a regression of respiratory failure and pulmonary hypertension.