The article deals with the pathophysiology of chronic obstructive pulmonary disease (COPD), modern possibilities of functional methods in COPD, including the diagnosis of small airway dysfunction and expiratory air flow limitation with quiet breathing by impulse oscillometry, and also describes the characteristic changes in the indicators of pulmonary functional tests in COPD.

Monitoring of the bioelectric activity of the hippocampal complex is performed according to the indications of patients with pharmacoresistant mesial temporal lobe epilepsy, who are indicated for surgical removal of the epileptic focus. The work was aimed at comparing the dynamics of the amplitude-frequency parameters of the bioelectrical activity of the hippocampal complex under the action of general anesthetics by comparing the parameters recorded before surgery and intraoperatively. The study included 8 patients with mesial temporal lobe epilepsy who, within the framework of pre-surgical planning, underwent invasive monitoring of the bioelectrical activity of the cortex and hippocampal com- plex, and then underwent surgical resection of the epileptic focus under general anesthesia with sevoflurane. Registration of 12 hippocampal tracks was carried out in dynamics: during extraoperative and intraoperative neurophysiological monitoring. In the state of calm wakefulness, the pattern of bioelectric activity of the hippocampal complex without structural changes was formed mainly by the activity of the alpha and theta frequency ranges. Under general anesthesia with sevoflurane, a slow-wave delta-range activity was recorded on the intraoperative ES- ubCoG. When the hippocampal complex was involved in the epileptic system, its activity in the state of passive wakefulness was represented by the slow-wave frequency range. Under the conditions of inhalation anesthesia with sevoflurane, the proportion of delta activity significantly decreased, and a state of dysrhythmia was observed without a clear dominance of activity in any range.

Purpose. To assess the systolic function of the right ventricle in patients with acute inferior myocardial infarction after percutaneous coronary intervention according to the results of echocardiographic examination.

Materials and methods. Echocardiographic data of 72 working-age patients with acute inferior myocardial infarction were analyzed. RV systolic function was assessed by TAPSE, S’TV, longitudinal strain of RV.

Results. In 37.5% of patients with AMI of the inferior wall, in 96% of cases by ECG (elevation of the ST segment in the first hours of the disease) and in 4% by echocardiography (impaired local contractility after PCI), RV AMI was diagnosed. After PCI, the medians of TAPSE and S’TV obtained in M- and pulsed- wave modes of tissue Doppler between the groups with isolated AMI (n=45) and RV involvement (n=27) did not differ from the control. Analysis of all walls of the RV and three segments its free wall obtained by speckle tracking technology demonstrates large changes in the longitudinal deformity of the RV with a combination of AMI of both ventricles. The minimum longitudinal deformity in the groups with AMI, statistically significantly different from the control group, was observed at the basal level of the free wall of the RV and the interventricular septum. Changes in the parameters of deformity of the apical segment were present only in AMI of both ventricles.

Conclusion. According to the results of echocardiographic examination in M-mode and pulsed-wave mode of tissue Doppler, the systolic function of the right ventricle in patients with acute inferior myocardial infarction both in combination with right ventricular infarction and in an isolated course a week after percutaneous coronary intervention corresponds to normal values. Using speckle tracking technology, the global longitudinal deformity of the right ventricle is not restored, remaining below the recommended norms and values of the control group in both AMI variants. The median of longitudinal deformity of the basal and median inferior septal segments had a minimum value (-9 and -12%) with combined lesions of both ventricles.

In 2019–2020, a large number of studies of pulse oximetry and computed tomography of the lungs were performed for the diagnosis of Covid-19. The analysis of the volume of pulse oximetry performed for 8 years from 2011 to 2019 increased by 8.5 times, and for one year from 2019 to 2020, the growth was 21.45 times, and the increase in pulse oximetry devices was 4.7 times.

The normative legal bases of the work of nursing staff of the departments (offices) of functional diagnostics (FD), as well as the most important issues of high-quality compliance with special manipulation techniques are presented. Effective ways of preventing and solving possible problems in the working conditions of medical organizations of the city of Moscow are given. The importance of maintaining high professional competencies of the secondary medical personnel of functional diagnostics departments (offices) is shown.

This article is the fifth and final part of a series of materials that tell about figurative comparisons and eponyms in modern functional diagnostics. Methods of clinical neurophysiology: electroencephalography, electromyography, stimulation electroneuromyography, surface electromyography, evoked potentials were considered. The names of great scientists who have made a great contribution to the history of medicine are given: Berger, Piper, Dawson. Figurative comparisons like, 'bioelectric silence', 'the sound of 'crumpling cellophane', 'printing on cardboard', 'the sound of a dive bomber', 'the sound of a mosquito buzzing', 'chess pattern', are described. The terms that will be discussed in the article have not only scientific, but also applied meaning. The article will be useful and interesting to students of medical universities, residents and doctors, whom it will help to check and, possibly, update their knowledge.