

The main modern methods of treatment of genitourinary menopausal syndrome
https://doi.org/10.33667/2078-5631-2025-7-16-21
Abstract
Symptoms of the genitourorinar menopausal syndrome appear simultaneously with vasomotor symptoms when menopause and even in perimenopause: soreness, itching and dryness in the vagina, dyspareunia, etc. This is due to the developmental atrophic changes in the urogenital tract, which sharply reduces the quality of life and is a risk factor for the development of recurrent infections of the genitourinary system. More than 65% of women in postmenopause without systemic menopausal hormonal therapy (MGT) suffer from manifestations of urogenital atrophy. This article discusses all modern methods of treating HUMS, describes various methods of treatment, their effectiveness, duration of application. As the first line of therapy, non -hormonal lubricants are recommended. With an average and severe degree of vulvovaginal atrophy and in the absence of contraindications, local intravaginal administration of estriol is used. The new promising methods of treatment with the State Unitary Enterprise are also described: Ospemicifen-oral, active selective selective modhertator of estrogen receptors (SERM), laser therapy, dehydroepiapianrosterone.
Conclusions. Genitouine menopausal syndrome – an underestimated common disease, but the frequency of use of local estrogens is low. Treatment should be continued for a long time to prevent relapse of the symptoms of Hums. Vaginal moisturizers can be used both in monotherapy and in combination with estriol.
About the Authors
E. V. TikhomirovaRussian Federation
Elena V. Tikhomirova - PhD Med, head of Dept of Nursing.
Moscow
V. E. Balan
Russian Federation
Vera E. Balan - DM Sci (habil.), professor, professor at Dept of Obstetrics and Gynecology.
Moscow
E. A. Chulkova
Russian Federation
Elena A. Tchoulkova - PhD Med, head of Dept of Internal Medicine.
Moscow
M. A. Orlyuk
Russian Federation
Maria A. Orlyuk - PhD Med, head of Dept of Surgical Diseases.
Moscow
O. V. Abanina
Russian Federation
Olga V. Abanina - PhD Med, dean of the Faculty of Medicine.
Moscow
E. K. Moiseeva
Russian Federation
Elena K. Moiseeva - head of Educational Programs of Secondary Vocational Education of the Faculty of Medicine.
Moscow
V. Ya. Yatsyuk
Russian Federation
Valentina Ya. Yatsyuk - Dr Pharmaceutical Sci, professor, professor at Dept of General and Bioorganic Chemistry.
Kursk
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Review
For citations:
Tikhomirova E.V., Balan V.E., Chulkova E.A., Orlyuk M.A., Abanina O.V., Moiseeva E.K., Yatsyuk V.Ya. The main modern methods of treatment of genitourinary menopausal syndrome. Medical alphabet. 2025;(7):16-21. (In Russ.) https://doi.org/10.33667/2078-5631-2025-7-16-21