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Seasonal coronaviruses and SARS-CoV-2: Structural, functional, clinical and epidemiological characteristics and humoral cross-immunity

https://doi.org/10.33667/2078-5631-2024-4-55-59

Abstract

It is assumed that the formation and persistence of immunity to SARS-CoV-2 may depend on the immune status of other infections caused by human coronaviruses (HCoV), called seasonal: HCoV-OC 43, HCoV-HKU 1, HCoV-229E, HCoV-NL63. These viruses are ubiquitous and typically cause mild to moderate seasonal respiratory illness. A comparative analysis of the main structural, functional, clinical and epidemiological characteristics of seasonal HCoV and SARS-CoV-2 is presented in the review. Systematization of this information in combination with data on cross-immunity to different HCoV may make it possible to identify factors of immunity to SARS-CoV-2 and take them into account when improving the strategy for sanitary and epidemiological control of COVID-19.

About the Authors

Yu. V. Shabalina
Altai State Medical University
Russian Federation

Shabalina Yulia V., senior lecturer at Dept of Biological Chemistry, Clinical Laboratory Diagnostics

Barnaul



S. A. Elchaninova
Altai State Medical University
Russian Federation

Elchaninova Svetlana A., DBio Sci (habil.), professor at Dept of Biological Chemistry, Clinical Laboratory Diagnostics

Barnaul



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Review

For citations:


Shabalina Yu.V., Elchaninova S.A. Seasonal coronaviruses and SARS-CoV-2: Structural, functional, clinical and epidemiological characteristics and humoral cross-immunity. Medical alphabet. 2024;(4):55-59. (In Russ.) https://doi.org/10.33667/2078-5631-2024-4-55-59

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