Effect of mini-gastric bypass surgery for morbid obesity on indicators of carbohydrate metabolism
https://doi.org/10.33667/2078-5631-2022-30-37-40
Abstract
Objective. To analyze the long-term results of the effect of mini-bypass surgery for morbid obesity on the state of carbohydrate metabolism and the dynamics of changes of BMI.
Materials and methods. A prospective uncontrolled randomized study was conducted on the basis of the Clinical Hospital ‘Russian Railways – Medicine’ of
City of Barnaul (Russia), which included patients aged 22 to 56 years with an average body mass index of 45.23 kg/m2 and having a violation of carbohydrate metabolism: 17 patients with an established diagnosis of type 2 diabetes, 20 patients with insulin resistance. Patients with DM were canceled prior to surgery and short-acting insulin preparations were prescribed situationally. Laparoscopic minigastric bypass surgery was performed, for which anesthesia with limited use of opioids was used. Indicators were determined: fasting blood glucose in the pre- and early postoperative period, after 6 months and 2 years, glycated hemoglobin, HOMA-IR index, BMI before surgery and in control measurements.
Results. The positive dynamics of the studied indicators was demonstrated in patients with impaired carbohydrate metabolism by the time of discharge from the hospital, which was performed on 4–5 days from the moment of surgery. In most patients, this trend persisted for 2 years after surgery. Positive changes in carbohydrate metabolism occurred against the background of a significant decrease of BMI.
Conclusions. Laparoscopic mini-bypass surgery is an effective method of treating morbid obesity with concomitant metabolic syndrome for a long time.
About the Authors
M. I. Neymark
Altai State Medical University
Russian Federation
Russian Federation
Neymark Mikhail I., DM Sci (habil.), professor, head of Dept of Anesthesiology, Resuscitation and Clinical Pharmacology with the course of additional professional education
Barnaul
A. A. Pantyushin
Altai State Medical University; Clinical Hospital ‘Russian Railways – Medicine’ of City of Barnaul
Russian Federation
Russian Federation
Pantyushin Aleksandr A., PhD Med, assistant at Dept of Faculty Surgery n. a. professor I. I. Neymark with the course of additional professional education, head of Surgical Dept
Barnaul
S. V. Zhilin
Clinical Hospital ‘Russian Railways – Medicine’ of City of Barnaul
Russian Federation
Russian Federation
Zhilin Sergei V., physician at Dept of Anesthesiology and Resuscitation
Barnaul
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For citations:
Neymark M.I., Pantyushin A.A., Zhilin S.V. Effect of mini-gastric bypass surgery for morbid obesity on indicators of carbohydrate metabolism. Medical alphabet. 2022;(30):37‑40. (In Russ.) https://doi.org/10.33667/2078-5631-2022-30-37-40
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