Reasons for mortality in elderly and senile patients with hip osteoporotic fractures
https://doi.org/10.33667/2078-5631-2019-2-37(412)-50-53
Abstract
Aim. To identify the causes of mortality in elderly and senile patients with non-traumatic hip fracture during the first year after fracture.
Materials and Methods. The reasons for death were analyzed in the cohort consisted of 432 patients with a non-traumatic hip fracture: 328 women aged from 70 to 82 years (mean age 75.4) and 104 men aged from 60 to 80 years (mean age 71.5).
Results. It was revealed that in first 6 months after the injury, death occurred in 22.00 % of cases (95 from 432 patients died). After 12 months period, mortality increased to 137 cases (total mortality accounted for 31.80 %). Most of the deaths were due to cardiovascular system diseases. Cardiovascular causes were in 93 cases (21.00 %), without any gender difference: 22 in men (21.10 %) and 71 in women 21.60 %). The ratio of cardiovascular diseases in the total number of fatal outcomes was 93 (67.80 %), comparable for men and women subgroups (66.00 and 68.30 % respectively; p = 0.65). Diseases of respiratory system as a reason for death accounted for 16.80 % in the structure of total mortality: 15.10 % in men subgroup and 17.30 % in women (p = 0.31). Mortality from tumors was defined in 10.90 % from all cases of death: in men 9.09 % cases and in women 11.50 % cases (p = 0.45). The ratio of digestive system disorders as the cause of death accounted for 3.60 %: 6.06 % in men and 2.90 % in women respectively (p = 0.1).
Conclusions. Cardiovascular and respiratory diseases were the most common causes of first-year mortality in elderly and senile patients with non-traumatic hip fracture. The gender differences in mortality rates were not found.
About the Authors
Yu. V. Averkieva
Kemerovo State Medical University
Russian Federation
Kemerovo
Russian Federation
Kemerovo
T. A. Raskina
Kemerovo State Medical University
Russian Federation
Kemerovo
Russian Federation
Kemerovo
I. I. Grigorieva
Kemerovo State Medical University
Russian Federation
Kemerovo
Russian Federation
Kemerovo
M. V. Letaeva
Kemerovo State Medical University
Russian Federation
Kemerovo
Russian Federation
Kemerovo
O. S. Malyshenko
Kemerovo State Medical University
Russian Federation
Kemerovo
Russian Federation
Kemerovo
References
1. Osteoporosis: a guide for doctors. Lesnyak OM, editor. Moscow: GEOTAR-Media Publ., 2016. 464 p. Russian (Остеопороз: руководство для врачей. под ред. О. М. Лесняк. — М.: ГЭОТАР-Медиа, 2016. 464 с.: ил. — ISBN 978–5–9704–3986–9).
2. Audit of the state of the problem of osteoporosis in the countries of Eastern Europe and Central Asia. Lesnyak OM, supervisor. Prepared by the International Osteoporosis Foundation // Naturaprint, 2011. Vol. 4 (5). P. 45–51. (Аудит состояния проблемы остеопороза в странах Восточной Европы и Центральной Азии. Лесняк О. М. Подготовлено Международным Фондом остеопороза // Naturaprint, 2011. Т. 4 (5). С. 45–51).
3. O’Neill TW, Roy DK. How many people develop fractures with what outcome? Best Pract Res Clin Rheumatol. 2005; 19: 879–8955.
4. Cree M, Soskolne CL, Belseck E, Hornig J, McElhaney JE, Brant R, Suarez-Almazor M. Mortality and institutionalization following hip fracture. J Am Geriatr Soc. 2000; 48: 283–8.
5. Tarazona-Santabalbina FJ, Belenguer-Varea A, Rovira-Daudi E, Salcedo-Mahiques E, Cuesta-Peredó D, Doménech-Pascual JR, Salvador-Pérez MI, Avellana-Zaragoza JA. Early interdisciplinary hospital intervention for elderly patients with hip fractures: functional outcome and mortality. Clinics (Sao Paulo). 2012; 67 (6): 547–56.
6. Center JR, Nguyen TV, Schneider D, Sambrook PN, Eisman JA. Mortality after all major types of osteoporotic fracture in men and women: an observational study. Lancet. 1999; 353 (9156): 878–82.
7. Browner WS, Pressman AR, Nevitt MC, Cummings SR. Mortality following fractures in older women. The study of osteoporotic fractures. Arch Intern Med. 1996; 156 (14): 1521–5.
8. Cummings SR, Melton LJ. Epidemiology and outcomes of osteoporotic fractures. Lancet. 2002; 359 (9319): 1761–7.
9. Abrahamsen B, van Staa T, Ariely R, Olson M, Cooper C. Excess mortality following hip fracture: a systematic epidemiological review. Osteoporos Int. 2009; 20 (10): 1633–50.
10. Kannegaard PN, van der Mark S, Eiken P, Abrahamsen B. Excess mortality in men compared with women following a hip fracture. National analysis of comedications, comorbidity and survival. Age Ageing. 2010; 39 (2): 203–9.
11. Сlinical guidelines. Osteoporosis: Diagnosis, prevention and treatment. Lesnyak OM, Benevolenskaya LI. Moscow: GEOTAR-Media Publ., 2011. 270 p. Russian (Клинические рекомендации. Остеопороз. Диагностика, профилактика и лечение / Лесняк О. М., Беневоленская Л. И. — М.: ГЭОТАР-Медиа, 2011. — 270 с.).
12. Kanis JA, Burlet N, Cooper C et al. European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos. Int, 2008; 19: 399–428.
13. Averkieva YV. Prevalence, risk factors and medico-social consequences of osteoporotic fractures in the residents of Kemerovo, the older age group. Cand. med. sci. abstracts diss. Krasnoyarsk, 2012. 26 p. Russian (Аверкиева ЮВ. Распространенность, факторы риска и медико-социальные последствия остеопоротических переломов у жителей г. Кемерово старшей возрастной группы: автореф. дис. … канд. мед. наук. Красноярск, 2012 г. 26 с.).
14. Diamantopoulos AP, Hoff M, Hochberg M, Haugeberg G. Predictors of Short- and Long-Term Mortality in Males and Females with Hip Fracture — A Prospective Observational Cohort Study. PLoS ONE. 8 (10): e78169. https: //journals.plos.org/plosone/article?id DOI: 10.1371/journal.pone.0078169.
15. Jetter AM, Harris BA. Functional recovery after hip fracture. Arch. Phys. Med. Rehabil., 1987; 68: 735–740.
16. Kimber C, Grimmer-Somers K. A novel primary care clinical prediction rule for early detection of osteoporosis. Aust. J. Prim. Health. 2011; 7 (2): 175–80. DOI: 10.1071/PY10045.
17. Lyons AR. Clinical outcomes and treatment of hip fractures. Am. J. Med. 1997; 103 (2A): 51–63.
18. Hu F, Jiang C, Shen J, Tang P, Wang Y. Preoperative predictors for mortality following hip fracture surgery: a systematic review and meta-analysis. Injury. 2012; 43 (6): 676–85.
19. L Riska BS, Forsén L, Omsland TK, Søgaard AJ, Meyer HE, Holvik K. Does the association of comorbidity with 1-year mortality after hip fracture differ according to gender? The Norwegian Epidemiologic Osteoporosis Studies (NOREPOS). J Am Geriatr Soc. 2018; 66 (3): 553–8.
20. Ha Y, Park Y, Nam KW, Kim S. Trend in hip fracture incidence and mortality in Korea: a prospective cohort study from 2002 to 2011. J Korean Med Sci. 2015; 30 (4): 483–8.
21. Bazhenova YuV, Menshikova LI, Pustozerov VG. A method for predicting osteoporotic vertebral fractures in elderly women: a method. recommendations. Irkutsk, 2008. 20 p. (Баженова Ю. В., Меньшикова Л. И., Пустозеров В. Г. Способ прогнозирования остеопоротических переломов позвонков у женщин пожилого возраста: метод. рекомендации / Иркутск, 2008. 20 с.)
22. Novack V, Jotkowitz A, Etzion О et al. Does delay in surgery after hip fracture lead to worse outcomes? A multicenter survey. Int. J. Qual. Health. Care. 2007; 19 (3): 170–176.
23. Prieto-Alhambra D, Avilés FF, Judge A at al. Burden of pelvis fracture: a population-based study of incidence, hospitalisation and mortality. Osteoporos Int. 2012. 23 (12): 2797–803.
24. Guzon-Illescas O, Perez Fernandez E, Crespí Villarias N, Quirós Donate FJ, Peña M, Alonso-Blas C, García-Vadillo A, Mazzucchelli R. Mortality after osteoporotic hip fracture: incidence, trends, and associated factors. J Orthop Surg Res. 2019 Jul 4; 14 (1): 203. DOI: 10.1186/s13018–019–1226–6. PMID: 31272470; PMCID: PMC 6610901.
25. Marchenkova LA, Dreval AV, Kryukova IV at al. Assessment of medical care for patients with osteoporosis based on the results of a survey of doctors in the Moscow region. Doctor. 2009; 11: 95–102. (Л. А. Марченкова, А. В. Древаль, И. В. Крюкова и др. Оценка медицинской помощи больным с остеопорозом по результатам анкетирования врачей Московской области // Врач. 2009; № 11. С. 95–102).
26. Ignacio Gonzalez-Montalvo J, Alarcon T, Hormigo Sanchez AI. Why do hip fracture patients die? Medicina Clinica. 2011; 137 (8): 355–60.
27. Von Friesendorff M, McGuigan FE, Wizert A et al. Hip fracture, mortality risk, and cause of death over two decades. Osteoporos Int. 2016; 27 (10): 2945–53.
Review
For citations:
Averkieva Yu.V., Raskina T.A., Grigorieva I.I., Letaeva M.V., Malyshenko O.S. Reasons for mortality in elderly and senile patients with hip osteoporotic fractures. Medical alphabet. 2019;2(37):50-53. (In Russ.) https://doi.org/10.33667/2078-5631-2019-2-37(412)-50-53
Views:
870
Email this article 