The analysis of scientific literature on the use of bisphosphonates in the treatment of osteoporosis. This effective group of drugs was included in the first line of appointments by specialists dealing with the problem of osteoporosis. At the same time, a number of authors associate the appearance of medicinal osteonecrosis of the jaws, called BONJ (bisphosphonate osteonecrosis of the jaws), in patients with the administration of bisphosphonates. One of the triggering mechanisms of the emergence of BONJ are surgical dental interventions performed in patients receiving bisphosphonates. Today, patients may not understand the seriousness of taking these drugs and often do not warn the dentist before manipulation, as well as not all dentists attach importance to the danger of drugs from osteoporosis. In this paper, based on the analysis of scientific literature, the attention of dentists to the problem of possible complications in the treatment of patients with osteoporosis, taking bisphosphonates. A questionnaire included in the questionnaire of a dental patient, taking into account the name of the drug and the duration of its administration, is proposed.

Тhe present article dwells upon the problem of the radiological diagnostics of the odontogenic jaw osteosteonecrosis, typical for the persons with the addiction to the drugs, containing phosphorus. Тhe research of the radiological evidence, typical for the aforesaid ailment is the goal of this article. Тhe patients are divided into 5 groups, the clinical situations are illustrated by radiographs, cone-beam and multispiral computer scans. Тhe signs discovered are applied as a basis for the rational surgical and medication treatment, and make it possible to differentiate between the odontogenic osteomyelitis of the commonplace etiology and desomorphine osteonecrosis as regards the patients with drug addiction.

The prevalence of benign tumors of the salivary glands is increasing. The complexity of the anatomical areas and the proximity of the of the facial nerve’s branches lead to frequent complications in the postoperative period. Nowadays there are several instrumental diagnostic methods for determining salivary gland tumors and among which the use of magnetic resonance imaging with contrast enhancement made it possible to estimate the exact location of neural and vascular structures in relation to the neoformation.

The article is devoted to the problem of efficiency improvement of the integrated treatment of exacerbation of chronic nonspecific sialadenitis in the patients of elder age groups. The results of clinical and immunological examination and treatment of 47 elderly and senile patients with exacerbation of chronic nonspecific sialadenitis are presented. Depression of the immune status components is revealed. It is shown that inclusion of polyoxidonium in the integrated treatment schedule of this pathology allows optimizing parameters of the local and systemic immunity, improving efficiency of the treatment, reducing patients' period of stay at in-patient hospital.

According to the results of studying cone-beam computed tomograms of the head of 147 people of the first period of adulthood with a full set of permanent teeth and physiological types of occlusion, the average inclinations of the incisors with respect to the occlusal plane and intercavity angles were calculated, and signs of a neutral position were formulated, physiological protrusion and physiological retrusion of incisors. It was revealed that the medial incisors of the upper jaw with the occlusal plane form an angle of 77.05 ± 0.70 degrees. For the neutral position of the incisors, the inclination angle varies from 75 to 80 degrees. A decrease in the incline angle of incisors in people with physiological types of occlusion of less than 75 degrees allowed the indicators to be considered as physiological protrusion, and an increase in the angle of more than 80 degrees characterized physiological retrusion. With the neutral position of the incisors, the intercavity angle averaged 135.49 ± 0.86 degrees. For the neutral position of the incisors, the value of the intersection angle varies from 125 to 145 degrees. The types of dental arches with the protrusive position of the incisors included variants in which the inter-incisal angle was less than 125 degrees. With the physiological retrusion of the incisors, the inter-incisal angle was more than 145 degrees. The results can be used as criteria for assessing the effectiveness of the treatment of patients with occlusion abnormalities.

The aim of the study was to study the bioelectric activity of the masticatory muscles in adult patients with defects in the dentition complicated by distal occlusion. The material of the study was the bioelectric activity indices of the masticatory muscles obtained by electromyography in 47 patients with defects in the dentition complicated by distal occlusion. As a result, according to electromyography, criteria for the adaptation of masticatory muscles to new conditions for the functioning of the masticatory apparatus formed as a result of treatment were identified. The revealed criteria make it possible to objectively determine the duration of the period of adaptation of the masticatory muscles at the stages of complex treatment of patients with this pathology.

The proposed article deals with a summary of characteristics of statistical data that illustrate sociological peculiarities specific for the elderly and senile patients who have sought prosthodontic treatment in the Municipal dental polyclinic in the city of Cheboksary. The article outlines the factors influencing the choice of a type of prosthetic dental restoration. All the described factors are given in an order of priority. Based on the public and social significance of the problem the authors show the relevance of the work on studying the oral health related quality of life of elderly people. The article describes the current population aging trend and peculiarities of the socialization of elderly people in the modern society. It also describes results of own studies encompassing a comparative analysis of social indicators of life of the elderly people in the city of Cheboksary in the Chuvash Republic which influence the choice of a type of prosthetic dental restoration.

The method of digital planning of sinus-lifting operation using the data of computed tomography, laser surface scanning of dentition, as well as a number of computer programs, the use of which in the treatment of tooth loss allows you to accurately determine the volume of bone-substituting material and the area of implant placement. This technique is based on the digital calculation of the volume of bone-substituting material required for introduction into the maxillary sinus during sinus-lifting operation.

This article is devoted to the question of one of the remote complications in dental implantology — fracture of the central screw of the abutment. Systematic studies of the influence of chemical and phase composition, volume and surface structure of products from titanium-based alloys on the functional properties of the «implant-screw-abutment» system, including corrosion resistance in biological media, have not been carried out. Therefore, the problem of establishing patterns of influence of these factors on the corrosion resistance of the elements of implantation systems, namely the central screw, and the study of its tribological properties (wear resistance), are relevant today.

The effect of enzymes carbohydrases exopolysaccharide matrix of biofilms formed by gram-positive and gram-negative bacteria on abiotic surfaces was studied. The ability of a mixture of carbohydrase enzymes (hydrolases and lyases) to completely destroy the matrix of biofilms formed by gram-positive and gram-negative bacteria causing health-associated infections has been confirmed. An optimal mixture of carbohydrases possesed high anti-biofilm activity even when employed in relatively small concentrations and at a brief exposure time.

Currently, to solve the bone deficiency problem in the maxillofacial region, osteoplastic materials based on allogeneic and xenogenic collagen bone matrix are used, both in pure and in activated forms, by adding growth factors. It is impossible to determine the effectiveness and mechanisms of the osteoplastic materials effect on bone regeneration without a comprehensive study, including not only histological, but also morphometric studies of the structural components and cellular reactions in the impact area. Such studies provide reliable and objective information on the main processes taking place in bone regeneration.

Purpose. To determine the spatial distribution of reparative osteogenesis in the presence of some osteoplastic materials in vitro.

Materials and methods. Svetlogorsk breed pigs were used as a biomodel. Depending on the osteoplastic preparations used, the animals were divided into four groups of the two in each: 1st — a preparation based on a natural bovine bone graft was injected into bone defects. 2nd — a preparation based on collagenized porcine transplant was injected into bone defects. 3rd — a preparation consisting of 60 % hydroxyapatite (HA) and 40 % beta-tri-calcium phosphate; 4th — control group — the bone defect healed under a blood clot. Animals were removed from the experiment on the 45th day. We examined sections with a thickness of 20 μm using the method of light and fluorescence microscopy.

Results. The results indicate different dynamics of the reparative osteogenesis in the presence of osteoplastic materials of different classes. In group 1, the filling of the defect with newly formed bone tissue is not uniform; in group 2, the filling of the defect with newly formed bone tissue is uniform; in group 3 the filling of the defect with non-formed bone tissue is uneven due to the pronounced hyperostosis; in the control group, the filling of the defect with newly formed bone tissue is not happening.

Conclusion. Stimulation, the dynamics of reparative osteogenesis and the three-dimensional organization of bone regenerate depend on the osteoplastic material class, which requires further study of the dynamics and three-dimensional organization of bone regenerate to select the optimal bone-replacing agent.