Practical approach to managing hemolyzed samples in laboratory
Abstract
The article describes a new approach to the assessment of hemolysis index (HI) on the example of two tests - alanine aminotransferase (ALT) and aspartate aminotransferase (AST), measured in blood serum samples on an automatic biochemical analyzer cobas 6000. This approach is based on the calculation of the Reference Change Value (RCV) taking into account the reference intervals for ALT and AST. This allows you to define a statistically significant the significance of differences between the two laboratory results from one patient and the deletion of obtaining false positive results.
About the Authors
O. A. Klimenkova
Consultative and Diagnostic Centre for Children
Russian Federation
Russian Federation
V. P. Pashkova
Consultative and Diagnostic Centre for Children
Russian Federation
Russian Federation
T. V. Vavilova
National Medical Research Centre n.a. V. A. Almazov
Russian Federation
Russian Federation
V. S. Berestovskaya
National Medical Research Centre n.a. V. A. Almazov
Russian Federation
Russian Federation
References
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Review
For citations:
Klimenkova O.A., Pashkova V.P., Vavilova T.V., Berestovskaya V.S. Practical approach to managing hemolyzed samples in laboratory. Medical alphabet. 2018;3(26):22-24. (In Russ.)
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