Indicators of heart rhythm variability, qt interval dispersion and late ventricultural potentials of patients with chronic renal insufficiency

Abstract

Objective: to study heart rate variability, QT interval dispersion and late ventricular potential of patients with chronic renal failure, depending on the stage of the disease and the presence of ventricular extrasystole. Materials and methods: 50 patients with terminal chronic renal insufficiency, on hemodialysis, 38 patients with stage III of chronic kidney disease and 20 healthy people have had 24-hour ECG monitoring with heart rate variability analysis, QT interval duration, QT interval variance and late potentials ventricles. Results: Patients with chronic renal insufficiency have shown a decrease in the overall heart rate variability, an increase in the activity of the sympathetic nervous system, an increase in the duration of the corrected QT interval, variance of the QT interval, and the presence of late ventricular potentials. The revealed disorders were increased in patients with terminal renal insufficiency and in patients with frequent ventricular extrasystole. Parameters of heart rate variability were closely correlated with the duration and variance of the QT interval, the indicators of late ventricular potentials. Gamma-correlation has established a direct relationship of frequent ventricular extrasystole with changes in electrophysiological indicators. Conclusion: vegetative imbalance, increased dispersion of the QT interval, and the presence of late ventricular potentials can be the predictors of ventricular rhythm disturbances of patients with chronic renal insufficiency.