Experience with the use of a pulsed dye laser in the treatment of patients with palmoplantar psoriasis
https://doi.org/10.33667/2078-5631-2026-3-80-82
Abstract
Palmoplantar psoriasis is a socially significant form of chronic dermatosis leading to a marked decrease in the quality of life and limitation of work activity. The search for effective and safe treatment methods, especially in the presence of contraindications to systemic therapy, remains relevant.
Objective. To evaluate the clinical efficacy and tolerability of pulsed dye laser in patients with palmoplantar psoriasis.
Material and methods. Two clinical cases are described. The first patient (61 years old) received a combination of topical therapy (salicylic acid, betamethasone) and a course of pulsed dye laser. The second case (a patient with controlled type 2 diabetes mellitus and intolerance to methotrexate) was treated with pulsed dye laser after discontinuation of the cytostatic agent. Efficacy was assessed by the dynamics of the palmoplantar psoriasis severity index (PPASI).
Results. Both patients showed significant positive dynamics. In the first case, the PPASI score decreased from 18 points to 1 point. In the second case, it decreased from 15 points to 0.5 points. There were no side effects from phototherapy.
Conclusion. Pulsed dye laser demonstrated high efficacy and good tolerability in the treatment of palmoplantar psoriasis. This method can be considered an optimal treatment option, especially in the presence of comorbid conditions that limit the use of systemic medications.
About the Authors
Ya. V. Kozyr
Clinical Dermatovenereology Dispensary
Russian Federation
Russian Federation
Kozyr Yana V., dermatovenereologist at Dept of Paid Medical Services
Krasnodar
M. S. Petrova
Central State Medical Academy of the Administrative Department of the President of the Russian Federation
Russian Federation
Russian Federation
Petrova Maria S., PhD Med Sci, associate professor at Department of Physical and Rehabilitation Medicine with a Course in Clinical Psychology and Pedagogy
Moscow
A. A. Khotko
Clinical Dermatovenereology Dispensary ; Central State Medical Academy of the Administrative Department of the President of the Russian Federation
Russian Federation
Russian Federation
Khotko Alkes A., Dr Med Sci (habil.), deputy chief physician for Medical Affairs, professor at Dept of Dermatovenereology and Cosmetology
Krasnodar; Moscow
E. A. Inyukhina
Clinical Dermatovenereology Dispensary
Russian Federation
Russian Federation
Inyukhina Elena A., dermatovenereologist, head of Dermatology Dept
Krasnodar
References
1. Kamiya K., Kishimoto M., Sugai J., Komine M., Ohtsuki M. Risk Factors for the Development of Psoriasis. Int J Mol Sci. 2019. Vol. 20, № 18. P. 4347. DOI: 10.3390/ijms20184347.
2. Kruglova L.S., Bakulev A.L., Korotaeva T.V., Lila A.M., Pereverzeva N.O. Psoriasis. GEOTAR-Media. 2022. 328 p. (In Russ.).
3. Kubanov A.A., Bogdanova E.V. Epidemiology of psoriasis in the Russian Federation (according to registry data) // Bulletin of Dermatology and Venereology. 2022. Vol. 98, № 1. P. 33–41.
4. Pettey A.A., Balkrishnan R., Rapp S.R., Fleischer A.B., Feldman S.R. Patients with palmoplantar psoriasis have more physical disability and discomfort than patients with other forms of psoriasis: implications for clinical practice // J Am Acad Dermatol. 2003. Vol. 49, № 2. P. 271–275.
5. Kholupova L.S., Kruglova L.S., Rudneva N.S., Bakulev A.L., Khotko A.A. Inverse psoriasis and psoriasis of “difficult” localizations: the efficacy of netakimab. Medical Alphabet “Dermatology” (2) MA No. 27 (521). 2022. P. 14–21. (In Russ.).
6. Vladimirova I.S., Kruglova L.S. Psoriasis and obesity. Long-term efficacy of the IL-23 inhibitor guselkumab: data from real-world clinical practice. Effective Pharmacotherapy. 2025. Vol. 21. No. 12. Pp. 38–48. (In Russ.).
7. Vladimirova I.S., Kruglova L.S. Psoriasis of special localizations and the efficacy of the IL-23 inhibitor guselkumab in clinical practice. Farmateka. 2024. Vol. 31. No. 10. Pp. 105–113. (In Russ.).
8. Hönigsmann H., Schwarz T. Ultraviolet therapy // In: Bolognia J.L., Jorizzo J.L., Schaffer J.V. (eds.). Dermatology. 3rd ed. Amsterdam: Elsevier, 2012. P. 2219–2235.
9. Potekaev N.N., Kruglova L.S. Laser in dermatology and cosmetology. Moscow. MDV. 2018. 280 p. (In Russ.).
Review
For citations:
Kozyr Ya.V., Petrova M.S., Khotko A.A., Inyukhina E.A. Experience with the use of a pulsed dye laser in the treatment of patients with palmoplantar psoriasis. Medical alphabet. 2026;(3):80-82. (In Russ.) https://doi.org/10.33667/2078-5631-2026-3-80-82
Views:
88
JATS XML
Email this article 