Coronary artery bypass grafting and mechanical circulatory support in penetrating cardiac injury: a clinical case
https://doi.org/10.33667/2078-5631-2025-35-7-10
Abstract
Objective. To describe a clinical case of venoarterial extracorporeal membrane oxygenation (VA-ECMO) used in a patient with a combination of penetrating cardiac injury, myocardial infarction, and emergency coronary artery bypass grafting (CABG).
Materials and methods. A 37-year-old male patient with a stab wound to the anterior chest wall complicated by hemopericardium, cardiogenic shock, and acute myocardial infarction is presented. Due to persistent systemic hemodynamic instability following initial surgical intervention, peripheral VA-ECMO was initiated, followed by emergency CABG.
Results. The use of VA-ECMO allowed hemodynamic stabilization and created optimal conditions for subsequent bypass surgery without aortic crossclamping. After 72 hours of support, positive dynamics were achieved, with recovery of left ventricular ejection fraction to 52% by the time of discharge.
Conclusion. This case demonstrates the potential effectiveness of VA-ECMO as a component of complex therapy in patients with combined cardiac injury. A multidisciplinary approach played a key role in achieving a favorable outcome.
About the Authors
N. S. ChibisovRussian Federation
Chibisov Nikita S., anesthesiologist and Intensive Care specialist
A. V. Vlasenko
Russian Federation
Vlasenko Alexey V., head of Anesthesiology and Intensive Care Dept No. 32
I. A. Glushenko
Russian Federation
Glushenko Igor A., head of Cardiac Surgery Dept No. 40
P. A. Zhezhuk
Russian Federation
Zhezhuk Pavel A., anesthesiologist and Intensive Care specialist
D. I. Levikov
Russian Federation
Levikov Dmitry I., head of Anesthesiology and Intensive Care Dept No. 52
A. G. Komarova
Russian Federation
Komarova Anna G., deputy chief physician for the Regional Vascular Center
E. P. Rodionov
Russian Federation
Rodionov Evgeny P., deputy chief physician for Anesthesiology and Intensive Care
References
1. Stretch R., Sauer C.M., Yuh D.D., Bonde P. National trends in the utilization of short-term mechanical circulatory support: incidence, outcomes, and cost analysis. J Am Coll Cardiol. 2014; 64 (14): 1407–1415. DOI: https://doi.org/10.1016/j.jacc.2014.07.958
2. Millar J.E., Fanning J.P., McDonald C.I. et al. The inflammatory response to extracorporeal membrane oxygenation (ECMO): a review of the pathophysiology. Crit Care. 2016; 20 (1): 387. DOI: https://doi.org/10.1186/s13054‑016‑1570‑4
3. Zangrillo A., Landoni G., Biondi-Zoccai G. et al. A meta-analysis of complications and mortality of extracorporeal membrane oxygenation. Crit Care Resusc. 2013; 15 (3): 172–178.
4. Extracorporeal Life Support Organization (ELSO). Guidelines for Adult Cardiac Failure, 5th edition. 2021. URL: https://www.elso.org/Portals/0/Files/elso_adult_cardiac_guidelines_2021_v1.4.pdf
5. Russo J.J., Aleksova N., Pitcher I. et al. Extracorporeal membrane oxygenation for massive pulmonary embolism. Can J Cardiol. 2021; 37 (3): 349–359. DOI: https://doi.org/10.1016/j.cjca.2020.08.028
6. ELSO Registry Data. Adult cardiac ECMO outcomes report. 2023. URL: https://www.elso.org/Registry/Statistics.aspx
7. Worku B., Gaudino M., Gulkarov I. et al. Bivalirudin versus heparin anticoagulation for extracorporeal membrane oxygenation. J Thorac Cardiovasc Surg. 2021; 161 (6): 2011–2022. DOI: https://doi.org/10.1016/j.jtcvs.2020.01.125
8. Harle H. et al. Peripheral ECMO cannulation: time to flow and complications. ASAIO J. 2022; 68 (2): 177–183. DOI: https://doi.org/10.1097/MAT.0000000000001444
9. Yeung J.H. et al. Outcomes after penetrating cardiac trauma: a multicenter study. Crit Care. 2020; 24 (1): 1–9. DOI: https://doi.org/10.1186/s13054‑020‑2781‑0
10. Hargrave J. et al. Predictors of mortality in penetrating cardiac injury. Ann Thorac Surg. 2021; 111 (1): 143–149. DOI: https://doi.org/10.1016/j.athoracsur.2020.04.041
11. ASAIO Guidelines 2023. Indications for Adult ECMO. ASAIO J. 2023; 69 (1): 1–15. DOI: https://doi.org/10.1097/MAT.0000000000001807
12. Peek G.J., Mugford M., Tiruvoipati R. et al. CESAR trial: ECMO versus conventional management for ARDS. Lancet. 2009; 374 (9698): 1351–1363. DOI: https://doi.org/10.1016/S0140-6736 (09) 61069‑2
13. Ouweneel D.M., Schotborgh J.V., Limpens J. et al. Percutaneous mechanical circulatory support versus intra-aortic balloon pump in cardiogenic shock: a meta-analysis. Lancet. 2017; 390 (10096): 1966–1974. DOI: https://doi.org/10.1016/S0140-6736 (17) 31778‑3
14. Tyburski J.G. et al. Cardiac valve and septal injuries after penetrating trauma. Ann Thorac Surg. 2020; 109 (3): 727–732. DOI: https://doi.org/10.1016/j.athoracsur.2019.08.097
15. Brathwaite C.E. et al. Electrocardiographic manifestations of penetrating cardiac trauma. Am J Emerg Med. 2020; 38 (12): 2626.e1–2626.e4. DOI: https://doi.org/10.1016/j.ajem.2020.06.045
16. Rali A.S. et al. Role of echocardiography in penetrating cardiac trauma. J Am Soc Echocardiogr. 2021; 34 (3): 295–302. DOI: https://doi.org/10.1016/j.echo.2020.11.017
17. Hajjar L.A., Teboul J. L. Mechanical circulatory support devices for cardiogenic shock: State of the art. Crit Care. 2021; 25 (): 1–12. DOI: https://doi.org/10.1186/s13054‑021‑03573‑9
18. Rajsic S., Treml B., Javor S. et al. Extracorporeal membrane oxygenation in trauma patients: a systematic review. Scand J Trauma Resusc Emerg Med. 2022; 30 (1): 1–10. DOI: https://doi.org/10.1186/s13049‑022‑00989‑8
19. Belohlavek J., Smalcova J., Rob D. et al. Effect of intra-arrest transport, extracorporeal CPR, and immediate invasive assessment on functional neurologic outcome in refractory OHCA. JAMA. 2022; 327 (8): 737–747. DOI: https://doi.org/10.1001/jama.2022.0310
20. Muller G., Flecher E., Lebreton G. et al. The ENCOURAGE mortality risk score and analysis of long-term outcomes after VA-ECMO for AMI-related cardiogenic shock. Intensive Care Med. 2016; 42 (3): 370–378. DOI: https://doi.org/10.1007/s00134‑015‑4206‑2
21. Bonello L., Delmas C., Schurtz G. et al. Mechanical circulatory support in patients with STEMI and cardiogenic shock: a position paper from the French Working Group on Acute Cardiac Care. Arch Cardiovasc Dis. 2018; 111 (10): 601–612. DOI: https://doi.org/10.1016/j.acvd.2018.04.005
22. Tonna J.E., Johnson N.J., Greenwood J. et al. Practice, outcomes and trends in the use of extracorporeal membrane oxygenation in adult patients supported in the United States: An analysis of the ELSO registry. Crit Care Med. 2020; 48 (7): 987–994. DOI: https://doi.org/10.1097/CCM.0000000000004363
23. Combes A., Brodie D., Bartlett R. et al. Position paper for the organization of ECMO programs for cardiac failure in adults. Intensive Care Med. 2016; 42 (5): 712–729. DOI: https://doi.org/10.1007/s00134‑016‑4273‑0
24. Lafç G., Budak A.B., Yener A.U. et al. Use of extracorporeal membrane oxygenation in adults. Heart Lung Circ. 2014; 23 (): 10–23. DOI: https://doi.org/10.1016/j.hlc.2013.08.013
25. Tzimas P. et al. Echocardiographic predictors of successful weaning from VA-ECMO in adult patients with cardiogenic shock. J Cardiothorac Vasc Anesth. 2021; 35 (8): 2277–2283. DOI: https://doi.org/10.1053/j.jvca.2021.01.013
26. Rao P., Khalpey Z., Smith R., Burkhoff D., Kociol R.D. Venoarterial extracorporeal membrane oxygenation for cardiogenic shock and cardiac arrest. Circ Heart Fail. 20184 11 (9): e004905. DOI: https://doi.org/10.1161/CIRCHEARTFAILURE.118.004905
27. Donker D.W., Brodie D., Henriques J.P., Broomé M. Left ventricular unloading during veno-arterial ECMO: a review of percutaneous and surgical unloading interventions. Perfusion. 2019; 34 (2): 98–105. DOI: https://doi.org/10.1177/0267659118812677
28. Makdisi G., Wang I. W. Extra corporeal membrane oxygenation (ECMO) review of a lifesaving technology. J Thorac Dis. 2015; 7 (7): E166–E176. DOI: https://doi.org/10.3978/j.issn.2072–1439.2015.07.17
29. Guglin M., Zucker M.J., Bazan V.M. et al. Venoarterial ECMO for adults: JACC Scientific Expert Panel. J Am Coll Cardiol. 2019; 73 (6): 698–716. DOI: https://doi.org/10.1016/j.jacc.2018.11.038
30. Thiele H., Ohman E.M., Desch S., Eitel I., de Waha S. Management of cardiogenic shock complicating myocardial infarction: an update 2019. Eur Heart J. 2019; 40 (32): 2671–2683. DOI: https://doi.org/10.1093/eurheartj/ehz363
31. Hochman J.S., Buller C.E., Sleeper L.A. et al. Cardiogenic shock complicating acute myocardial infarction–etiologies, management and outcome: a report from the SHOCK Trial Registry. J Am Coll Cardiol. 2000; 36 (3 Suppl A.): 1063–1070. DOI: https://doi.org/10.1016/S0735–1097(00)00878-X
32. Rastan A.J., Dege A., Mohr M. et al. Early and late outcomes of 517 consecutive patients treated with extracorporeal membrane oxygenation for refractory postcardiotomy cardiogenic shock. J Thorac Cardiovasc Surg. 2010; 139 (2): 302–311. DOI: https://doi.org/10.1016/j.jtcvs.2009.10.043
33. Burrell A.J.C., Pellegrino V.A., Wolfe R. et al. Outcomes of patients treated with V-A ECMO for cardiogenic shock and cardiac arrest in Australia and New Zealand. Intensive Care Med. 2021; 47 (6): 674–686. DOI: https://doi.org/10.1007/s00134‑021‑06394‑0
Review
For citations:
Chibisov N.S., Vlasenko A.V., Glushenko I.A., Zhezhuk P.A., Levikov D.I., Komarova A.G., Rodionov E.P. Coronary artery bypass grafting and mechanical circulatory support in penetrating cardiac injury: a clinical case. Medical alphabet. 2025;(35):7-10. (In Russ.) https://doi.org/10.33667/2078-5631-2025-35-7-10
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