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Late urinary toxicity following radiation in prostate cancer: literature review
https://doi.org/10.33667/2078-5631-2025-14-31-37
Abstract
Introduction. Radiation damage to the bladder is one of the most common complications of radiation therapy for pelvic malignancies.
Materials and methods. The search, analysis and systematization of relevant publications in databases were carried out. e.Library.ru, cyberleninka.ru, PubMed. 64 articles were selected, which are included in this review.
Results and discussion. Data on epidemiology, risk factors, pathogenesis, prevention, diagnosis, and treatment of radiation damage to the bladder are presented.
Conclusions. Hyperbaric oxygenation, intravesical instillation of glycosaminoglycan acid and chondroitin sulfate, as well as transurethral fulguration remain the most effective methods of treating radiation damage to the bladder.
About the Authors
D. M. Monakov
Vishnevsky National Medical Research Center of Surgery; Peoples’ Friendship University named after Patrice Lumumba
Russian Federation
Russian Federation
Dmitry M. Monakov, PhD Med, senior researcher, associate professor
Dept of urology and surgical nephrology with a course in oncourology
Moscow
РИНЦ Author ID 995385
M. Yu. Kukosh
Peoples’ Friendship University named after Patrice Lumumba; Medical Radiological Scientific Center named after A. F. Tsyba – a branch of the National Medical Research Center of Radiology; MELANOMA UNIT СLC
Russian Federation
Russian Federation
Maria Yu. Kukosh, PhD Med, associate professor, senior researcher, medical oncologist
Dept of Oncology and Hematology
Moscow; Obninsk
РИНЦ AuthorID 824956
O. M. Zimovets
Vishnevsky National Medical Research Center of Surgery
Russian Federation
Russian Federation
Oksana M. Zimovets, resident in the specialty “Urology”
Moscow
A. A. Gritskevich
Vishnevsky National Medical Research Center of Surgery; Peoples’ Friendship University named after Patrice Lumumba
Russian Federation
Russian Federation
Alexandr A. Gritskevich, DM Sci (habil.), head of Dept, professor
Dept of oncourology and urology; Dept of Urology and Surgical Nephrology with a Course in Oncourology
Moscow
РИНЦ AuthorID:816947
A. B. Bogdanov
Russia Moscow Multidisciplinary Scientific and Clinical Center named after S. P. Botkin; Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
Andrey B. Bogdanov, PhD Med, urologist, associate professor
Urology Dept; Dept of Urology and Surgical Andrology
Moscow
M. D. Ter-Ovanesov
Peoples’ Friendship University named after Patrice Lumumba
Russian Federation
Russian Federation
Mikhail D. Ter-Ovanesov, DM Sci (habil.), professor, head of Dept
Dept of Oncology and Hematology
Moscow
РИНЦ AuthorID 698259
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For citations:
Monakov D.M., Kukosh M.Yu., Zimovets O.M., Gritskevich A.A., Bogdanov A.B., Ter-Ovanesov M.D. Late urinary toxicity following radiation in prostate cancer: literature review. Medical alphabet. 2025;(14):31-37. (In Russ.) https://doi.org/10.33667/2078-5631-2025-14-31-37
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