Clinical case of small cell neuroendocrine laryngeal cancer

Small-cell laryngeal carcinoma is a rare and highly aggressive tumor with significant potential for metastasis. Given its biological characteristics, this disease should be considered as disseminated at the stage of primary diagnosis. Currently, about 700 cases of neuroendocrine neoplasms of the larynx have been described in the literature. According to the largest study involving 436 patients, chemoradiotherapy is one of the most effective treatment methods, which leads to an increase in progression-free time compared to other methods. This article presents a clinical case of treatment of a patient with small cell neuroendocrine laryngeal cancer with damage to regional lymph nodes who received chemoradiotherapy in combination with chemotherapy according to the CAV scheme, with the maximum effect of treatment in the form of complete regression.

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