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Principles of quality management in conducting forensic biological examination of material evidence
https://doi.org/10.33667/2078-5631-2025-5-58-63
Abstract
The publication describes a method for conducting intra-laboratory quality control when determining various levels of PSA and IgG concentrations in aqueous extracts from semen and blood stains dried on gauze by quantitative enzyme immunoassay, used to determine the presence of sperm and blood species. It has been established that in-laboratory quality control of samples obtained as a result of measuring the concentration of PSA and IgG in duplicates is rationally carried out using the Dahlberg formula, which makes it possible to calculate the indicators of standard uncertainty: SD and CV%. As a result of the conducted study of the quality of interpretation of measurement results in aqueous extracts from semen and blood stains by quantitative enzyme immunoassay using a consistent Clark error grid, data on the acceptable error value for zone «A» were obtained, which can be taken into account when conducting forensic examinations of material evidence.
About the Authors
V. L. Sidorov
Bureau of Forensic Medical Examination
Russian Federation
Russian Federation
Sidorov Vladimir L., PhD Bio Sci, forensic expert at Forensic Biology Dept.
St. Petersburg
O. D. Yagmurov
Bureau of Forensic Medical Examination
Russian Federation
Russian Federation
Yagmurov Orazmurad D., DM Sci (habil.), professor, head.
St. Petersburg
K. T. Momynaliev
All-Russian Scientific Research and Testing Institute of Medical Technology of the Federal Service for Healthcare Supervision
Russian Federation
Russian Federation
Momynaliev Kuvat T., Dr Bio Sci, associate professor, assistant to the general director
St. Petersburg
V. L. Emanuel
I. P. Pavlov First St. Petersburg State Medical University (Pavlov University)
Russian Federation
Russian Federation
Emanuel Vladimir L., DM Sci (habil.), professor, head of Dept of Clinical Laboratory Diagnostics with a Course in Molecular Medicine3, director of the Scientific and
Methodological Center for Molecular Medicine of the Ministry of Health of the Russian Federation
St. Petersburg
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Review
For citations:
Sidorov V.L., Yagmurov O.D., Momynaliev K.T., Emanuel V.L. Principles of quality management in conducting forensic biological examination of material evidence. Medical alphabet. 2025;(5):58-63. (In Russ.) https://doi.org/10.33667/2078-5631-2025-5-58-63
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