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Features of the interpretation of laboratory parameters in tuberculosis: a systematic review
https://doi.org/10.33667/2078-5631-2025-5-47-52
Abstract
The objective of the study is to conduct a systematic review of the role of molecular genetic methods in the laboratory diagnosis of tuberculosis. The review covers methods such as polymerase chain reaction (PCR), drug resistance detection tests (GeneXpert), and sequencing. The analysis highlights the advantages of these methods compared to traditional diagnostic techniques like microscopy and culture methods. The study also addresses the challenges and prospects of implementing molecular diagnostics in clinical practice. A comprehensive approach was used to gather data from scientific databases (Scopus, Web of Science, MedLine, and others). The main results confirm the high sensitivity and specificity of molecular methods, making them an essential part of modern tuberculosis diagnostics. Conclusions emphasize the need for further integration of molecular technologies with traditional approaches to enhance disease diagnosis and treatment.
About the Author
A. I. Sereda
Moscow regional Clinical Tuberculosis Dispensary
Russian Federation
Russian Federation
Sereda Alina I., doctor of clinical laboratory diagnostics of the 1st category
Moscow
References
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Review
For citations:
Sereda A.I. Features of the interpretation of laboratory parameters in tuberculosis: a systematic review. Medical alphabet. 2025;(5):47-52. (In Russ.) https://doi.org/10.33667/2078-5631-2025-5-47-52
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