Severe vomiting of pregnant women, complicated by Wernicke’s encephalopathy (clinical observation)
Abstract
The article describes the clinical observations of pregnant woman with severe vomiting, complicated by Wernicke’s encephalopathy (WE). The cause of this pathology is a deficiency of vitamin B 1, which is rare in socially adapted persons. The authors noted high mortality in WE (20%), due to the delay in diagnosis and early treatment. Clinical observation of EV in pregnant woman with a lesion of the oculomotor and bulbar nerves is confirmed by the data of roentgenotomography. The authors described the classic triad of WE, the order of onset and regression of symptoms. Special attention is paid to the treatment of EV. Immediate treatment with thiamine should be started within 48-72 hours after the first symptoms. The authors mention the literary and own data about the necessity of application of high doses of thiamine by parenteral route. In the future, the patient should be administered long-term vitamin B complex. Prognosis of WE depends on the timing of the start of treatment. Even in this case atactic disorders remain long.
About the Author
S. R. Mravyan
Moscow Regional Research Institute for Obstetrics and Gynecology
Russian Federation
Russian Federation
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For citations:
Mravyan S.R. Severe vomiting of pregnant women, complicated by Wernicke’s encephalopathy (clinical observation). Medical alphabet. 2017;4(37):32-36. (In Russ.)
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