Interrelation of matrix metalloproteinases level with different forms of cleft lip and palate
Abstract
Congenital cleft lip and palate is one of the worlds commonest developmental defects. At present, there are efficacious surgical techniques designed to correct this congenital pathology in the maxillofacial region. However, the primary surgical intervention time is controversial. In our investigation, we studied the activity of matrix metalloproteinases in soft tissues cleft and lip of children with CLP. Our observation data led us to the conclusion that earlier operative times contributed to better physiological and functional restoration of soft labial and palatine tissues.
About the Authors
A. E. Mardanov
First Moscow State Medical University n.a. I. M. Sechenov
Russian Federation
Russian Federation
A. A. Mamedov
First Moscow State Medical University n.a. I. M. Sechenov
Russian Federation
Russian Federation
N. S. Morozova
First Moscow State Medical University n.a. I. M. Sechenov
Russian Federation
Russian Federation
L. A. Mazurina
First Moscow State Medical University n.a. I. M. Sechenov
Russian Federation
Russian Federation
O. T. Zangiev
First Moscow State Medical University n.a. I. M. Sechenov
Russian Federation
Russian Federation
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Review
For citations:
Mardanov A.E., Mamedov A.A., Morozova N.S., Mazurina L.A., Zangiev O.T. Interrelation of matrix metalloproteinases level with different forms of cleft lip and palate. Medical alphabet. 2017;4(36):28-35. (In Russ.)
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