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Optimization of the method of introducing anti-adhesion gel “Аntiadhesin” during laparoscopic access in gynecology

https://doi.org/10.33667/2078-5631-2024-8-8-12

Abstract

Optimization of the method of introducing an anti-adhesive barrier during laparoscopic operations allows surgeons to freely use an anti-adhesive barrier – «Аntiadhesin» – in their practice in order to prevent the occurrence of postoperative adhesions.

Target. To conduct a comparative study of various methods of local delivery of the anti-adhesion gel ‘Antiadgesin” to the abdominal and pelvic organs during laparoscopic interventions in gynecology.

Materials and methods of research. An analysis of 442 cases of laparoscopic operations, 90 cases of operations with laparotomic access and 180 hysteroscopic interventions was carried out, in which Antiadgesin was delivered to the wound surfaces using various conduction systems (applicators). The studies were conducted at the clinical base of the Department of Obstetrics and Gynecology No. 2 of the Stavropol State Medical University, in the department of operative gynecology from 2020 to 2023.

Results. In the course of the study, the effectiveness of using a disposable silicone conductor (applicator) 27 cm long, with an outer diameter of 4 mm and an internal diameter of 3 mm, was established for targeted local delivery of anti-adhesive gel “Antiadgesin” to all hard-to-reach areas of the abdominal cavity and pelvis (including in obese patients). Local targeted delivery allows you to effectively use the volume of gel supplied in the syringe, covering all necessary wound surfaces.

About the Author

A. A. Grigoryants
Stavropol State Medical University
Russian Federation

Grigoryants Armen A., PhD Med, assistant,

Stavropol.



References

1. Abakumov M.M., Adamyan A.A., Akchurin R.S. and others. 80 lectures on surgery / edited by. ed. V.S. Savelyeva. M.: Litterra, 2019. 912 p.

2. Zeng Q., Yu Z., You J., Zhang Q. Efficacy and safety of Seprafilm for preventing postoperative abdominal adhesion: systematic review and metaanalysis. World J. Surg 2017; 31: 2125–2131.

3. Gonzalez-Quintero VH, Cruz-Pachano FE. Preventing adhesions in obstetric and gynecologic surgical procedures. Rev. Obst. Gyn. 2019; 2 (1): 38–45.

4. Hirota Y., Tsukada K., Nishio E. Postoperative adhesion formation after laparoscipic uterine horn resection in a porcine model: comparison of five instruments. J. Laparoendosc Adv. Surg. Tech. A2021; 15: 581–585.

5. Acunzo G, Acunzo G, Guida M, Pellicano M, Tommaselli GA, Di Spiezio Sardo A, Bifulco G, Cirillo D, Taylor A, Nappi C. Effectiveness of auto-cross-linked hyaluronic acid gel in the prevention of intrauterine adhesions after hysteroscopicadhesiolysis: a prospective, randomized, controlled study. Hum. Reprod. 2013; 18 (9): 1918–1921.

6. Awonuga AO, Fletcher NM, Saed GM, Diamond MP. Postoperative adhesion development following cesarean and open intra-abdominal gynecological operations: a rewiew. Reprod. Sci. 2019; 18 (12): 1166–1185.

7. Lundorff P, Hahlin M, Källfelt B, Thorburn J, Lindblom B. Adhesion formation after laparoscopic surgery in tubal pregnancy: a randomized trial versus laparotomy. Fertil. Steril. 2019; 55 (5): 911–915. http://dx.doi.org/10.1016/S0015–0282(16)54298–8

8. The Use of Adhesion Prevention Agents in Obstetrics and Gynaecology. Royal College of Obstetricians and Gynecologists. 2020. Scientific Impact Paper. No. 39. 6 p.

9. Bezhenar V. F., Tsypurdeeva A.A., Baylyuk E.N. Adhesive disease of the pelvic organs in gynecological patients: from pathogenesis to practice. Oncogynecology. 2019; 4: 68–74.

10. AAGL Practice Report: Practice Guidelines for Management of Intrauterine Synechiae. 2018; 8.

11. Zeng Q., Yu Z., You J., Zhang Q. Efficacy and safety of Seprafilm for preventing postoperative abdominal adhesion: systematic review and metaanalysis. World J. Surg. 2021; 31: 2125–2131.


Review

For citations:


Grigoryants A.A. Optimization of the method of introducing anti-adhesion gel “Аntiadhesin” during laparoscopic access in gynecology. Medical alphabet. 2024;(8):8-12. (In Russ.) https://doi.org/10.33667/2078-5631-2024-8-8-12

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)