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Palliative surgical treatment in patients with breast cancer

https://doi.org/10.33667/2078-5631-2023-36-18-23

Abstract

Last many years breast cancer on a leading position in the structure of oncological pathology among the female population. Patients with metastatic breast cancer, as well as with the presence of tumors with incipient decay or bleeding, are currently considered as patients for complex palliative systemic treatment. The question of the expediency of performing an operation in such a pathology occurs quite often in the daily practice of an oncologist-surgeon. Of course, such life-threatening conditions as decaying breast tumors, bleeding from them, do not raise doubts about the urgency of providing palliative surgical treatment, which is often it is sanitation mastectomy. However, the need for a surgical stage of treatment in the complex palliative therapy of metastatic breast cancer raises many questions. The possibilities of treating metastatic breast cancer have expanded significantly due to the development of drug therapy regimens, up to treating it as a chronic disease. The success of drug breast cancer treatment gives a chance to prolong the life of patients for many years. Thus, in the process of long-term treatment of these patients, various situations arise that require an individual solution. Based on the results of studies, the authors conclude that the decision to remove the primary breast lesion in such patients should be individualized and based on the opinion of the oncologist-surgeon, chemotherapist and radiation therapist, taking into account the potential risk, as well as the subsequent quality of life. In addition, as it turned out, the surgical stage of treatment in such patients not only improves the subsequent quality of life, but also improves oncological indicators. This article discusses the indications and contraindications for performing palliative surgical treatment of patients with breast cancer, based on world studies and our own experience and a clinical study.

About the Authors

I. M. Onofriychuk
Moscow Research Institute of Oncology n. a. P.A. Herzen – a Branch of the National Medical Research Centre of Radiology; Peoples’ Friendship University of Russia n. a. Patrice Lumumba
Russian Federation

Onofriychuk Irina M. - PhD Med, researcher at Dept of Reconstructive Plastic Surgery of Skin and Breast MRIO n. a. P.A. Herzen – a Branch of the NMRCR, assistant at Dept of Oncology and Radiology PFUR n. a. Patrice Lumumba.

Moscow



A. D. Zikiryahodzhaev
Moscow Research Institute of Oncology n. a. P.A. Herzen – a Branch of the National Medical Research Centre of Radiology; Peoples’ Friendship University of Russia n. a. Patrice Lumumba; First Moscow State Medical University n. a. I.M. Sechenov
Russian Federation

Zikiryakhodzhaev Aziz D. - DM Sci (habil.), head of Dept of Reconstructive Plastic Surgery of Skin and Breast MRIO n. a. P.A. Herzen – a Branch of the NMRCR, professor at Dept of Oncology and X-ray Radiology PFUR n. a. Patrice Lumumba, associate professor at Dept of Oncology FMSMU n. a. I.M. Sechenov.

Moscow



Sh. G. Khakimova
Moscow Research Institute of Oncology n. a. P.A. Herzen – a Branch of the National Medical Research Centre of Radiology; Tashkent Pediatric Medical Institute
Uzbekistan

Khakimova Shakhnoz G. - PhD Med, trainee at Dept of Reconstructive Plastic Surgery of Skin and Breast MRIO n. a. P.A. Herzen – a Branch of the NMRCR, associate professor at Dept of Pediatric Oncology Tashkent PMI.

Moscow, Tashkent



E. K. Saribekyan
Moscow Research Institute of Oncology n. a. P.A. Herzen – a Branch of the National Medical Research Centre of Radiology
Russian Federation

Saribekyan Erik K. - DM Sci (habil.), senior researcher at Dept of Reconstructive Plastic Surgery of Skin and Breast.

Moscow



G. M. Zapirov
Peoples’ Friendship University of Russia n. a. Patrice Lumumba
Russian Federation

Zapirov Gadzhimurad M., PhD Med, associate professor at Dept of Oncology and X-ray Radiology.

Moscow



G. G. Khakimova
Tashkent Pediatric Medical Institute; Tashkent City Branch of the Republican Specialized Scientific and Practical Medical Centre of Oncology and Radiology
Uzbekistan

Khakimova Gulnoz G. - PhD Med, associate professor at Dept of Pediatric Oncology Tashkent PMI, Oncologist Tashkent City Branch of the RSSPMCOR.

Tashkent



A. S. Sukhotko
City Clinical Hospital n. a. S.P. Botkin
Russian Federation

Sukhotko Anna S. - PhD Med, oncologist.

Moscow



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Review

For citations:


Onofriychuk I.M., Zikiryahodzhaev A.D., Khakimova Sh.G., Saribekyan E.K., Zapirov G.M., Khakimova G.G., Sukhotko A.S. Palliative surgical treatment in patients with breast cancer. Medical alphabet. 2023;(36):18-23. (In Russ.) https://doi.org/10.33667/2078-5631-2023-36-18-23

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)