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Difficulties in differential diagnosis of myasthenia gravis (clinical case)

https://doi.org/10.33667/2078-5631-2022-32-13-16

Abstract

Myasthenia gravis is a rare autoimmune disease, the clinical picture of myasthenia gravis is manifested by fluctuating weakness, pathological muscle fatigue and it is difficult for clinicians to diagnose it appropriately. The article presents a clinical case of misdiagnosis of late-onset myasthenia gravis, it provides a chronology of the development of symptoms of the disease and an analysis of the difficulties of differential diagnosis. Despite the typical manifestations of myasthenia gravis, the patient did not receive propriate pathogenetic therapy for a long time, while he was prescribed drugs that block neuromuscular conduction and worsen the course of the disease.

About the Authors

S. V. Lobzin
North-Western State Medical University n. a. I. I. Mechnikov
Russian Federation

Lobzin Sergei V., DM Sci (habil.), professor, head of Dept of Neurology n. a. academician S. N. Davidenkov. eLibrary SPIN: 7274–6327

St. Peterburg



A. R. Alibekov
North-Western State Medical University n. a. I. I. Mechnikov; Vsevolozhsk Clinical Interdistrict Hospital
Russian Federation

Alibekov Ailer R., postgraduate student of Dept of Neurology n. a. academician S. N. Davidenkov, neurologist. eLibrary SPIN: 1112–9540

St. Peterburg

Vsevolozhsk



E. G. Klocheva
North-Western State Medical University n. a. I. I. Mechnikov
Russian Federation

Klocheva Elena G., DM Sci (habil.), professor at Dept of Neurology n. a. academician S. N. Davidenkov. eLibrary SPIN: 6220–5349

St. Peterburg



A. L. Sharapova
Novgorod Regional Clinical Hospital
Russian Federation

Sharapova Anna L., neurologist at Dept of Neurology

Velikiy Novgorod



V. V. Goldobin
North-Western State Medical University n. a. I. I. Mechnikov
Russian Federation

Goldobin Vitaliy V., DM Sci (habil.), professor, head of Dept of Neurology n. a. academician S. N. Davidenkov. eLibrary SPIN: 4344–5782

St. Peterburg



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Review

For citations:


Lobzin S.V., Alibekov A.R., Klocheva E.G., Sharapova A.L., Goldobin V.V. Difficulties in differential diagnosis of myasthenia gravis (clinical case). Medical alphabet. 2022;1(32):13-16. (In Russ.) https://doi.org/10.33667/2078-5631-2022-32-13-16

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)