Features of diagnosis of generalized forms of meningococcal infection at present stage
M. V. Nagibina,
Yu. Ya. Vengerov,
V. A. Kadyshev,
N. E. Sukhoparova,
T. S. Svistunova,
T. Yu. Smirnova,
O. A. Tishkevich,
M. S. Gontarenko https://doi.org/10.33667/2078-5631-2022-23-10-14
Abstract
Despite the low level of morbidity, the significance of meningococcal infection (MI) persists and is primarily due to the predicted rise in morbidity after a long period of relative well-being (decline), instability of the serogroup landscape, an increase in morbidity caused by previously rare serotypes (meningococcus W), lack of routine vaccination, as well as severe course, the development of formidable complications and high risk of death. The risk of up to 30–60 % disabling complications after generalized forms of meningococcal infection (GFMI), including physical and neuropsychiatric problems, is also important. The reason for the unfavorable prognosis of the disease is the late diagnosis at the pre-hospital stage, hospitalization in non-core hospitals, the severity of the pathological process. With a low incidence, a wide range of antibacterial drugs, the mortality from GFMI is significant, from 6 to 14 %. The main means to significantly reduce the incidence and mortality from GFMI is currently the introduction of mass vaccination of the population against MI.
About the Authors
M. V. Nagibina
Moscow State University of Medicine and Dentistry n.a. A. I. Evdokimov
Russian Federation
Russian Federation
Nagibina Margarita V., DM Sci (habil.), professor at Infectious Diseases and Epidemiology Dept
Moscow
Yu. Ya. Vengerov
Moscow State University of Medicine and Dentistry n.a. A. I. Evdokimov
Russian Federation
Russian Federation
Vengerov Yuri Ya., DM Sci (habil.), professor at Infectious Diseases and Epidemiology Dept
Moscow
V. A. Kadyshev
Ambulance and Medical Emergency Care Station n.a. A. S. Puchkov; Moscow State University of Medicine and Dentistry n.a. A. I. Evdokimov
Russian Federation
Russian Federation
Kadyshev Valery A., PhD Med, head of Organizational and Methodological Dept of Emergency Medical Care; associate professor at Dept of Emergency Medical Care of Medicine Faculty
Moscow
N. E. Sukhoparova
Infectious Clinical Hospital No. 2
Russian Federation
Russian Federation
Sukhoparova Natalia E., intensive care doctor of ICU
Moscow
T. S. Svistunova
Infectious Clinical Hospital No. 2
Russian Federation
Russian Federation
Svistunova Tatiana S., PhD Med, head of Bacteriology Laboratory
Moscow
T. Yu. Smirnova
Infectious Clinical Hospital No. 2
Russian Federation
Russian Federation
Smirnova Tatiana Yu., head of Neuroinfection Dept
Moscow
O. A. Tishkevich
Infectious Clinical Hospital No. 2
Russian Federation
Russian Federation
Tishkevich Oleg A., doctor of Dept of Pathomorphology
Moscow
M. S. Gontarenko
Infectious Clinical Hospital No. 2
Russian Federation
Russian Federation
Gontarenko Marina S., head Clinical and Diagnostic Laboratory
Moscow
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Review
For citations:
Nagibina M.V., Vengerov Yu.Ya., Kadyshev V.A., Sukhoparova N.E., Svistunova T.S., Smirnova T.Yu., Tishkevich O.A., Gontarenko M.S. Features of diagnosis of generalized forms of meningococcal infection at present stage. Medical alphabet. 2022;(23):10-14. (In Russ.) https://doi.org/10.33667/2078-5631-2022-23-10-14
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