Artifcial intelligence capabilities in evaluating effectiveness of non-medicinal treatment of obesity in children
https://doi.org/10.33667/2078-5631-2022-18-20-24
Abstract
Introduction. Non-drug therapy for obesity cannot always guarantee a positive result, which forces doctors and scientists from all over the world to look for new methods for analyzing the effectiveness of treatment, including using artifcial intelligence. Its active implementation can significantly improve the quality of diagnosis and prognosis of the disease. Purpose of the study. To evaluate the possibilities of using the artifcial intelligence system in predicting the effectiveness of non-drug therapy for obesity in children.
Materials and methods. An artifcial neural network was built using the Statistica Neural Networks software package based on data from patients who were hospitalized at the Voronezh Children's Clinical Hospital of the VSMU n.a. N.N. Burdenko.
Results. The study group included 60 children (30 boys and 30 girls), aged 8 to 16 years. We selected the parameters that, in our opinion, have the most signifcant impact on the effect of non-drug treatment of obesity: the presence and frequency of inpatient treatment; obesity complications; compliance with the regime of physical activity and dietary recommendations; dynamics of body weight during non-drug treatment. After training, the neural network MLP 5-5-1 was selected with determination coeffcients of 0.925231; 0.981940; 0.936712 for training, test and control samples. The learning error is 0.105782, the learning algorithm is BFGS. The activation function of hidden neurons is hyperbolic, and the output function is identical.
Conclusion. The results of the study show that an artifcial neural network can be used to evaluate the effectiveness of non-drug treatment with a minimum error.
About the Authors
T. V. ChubarovRussian Federation
Chubarov Timofei V., PhD Med, chief physician of Voronezh Children's Clinical Hospital, director of Endocrinological Centre
Voronezh
O. A. Zhdanova
Russian Federation
Zhdanova Olga A., DM Sciences (habil.), associate professor at Dept of Clinical Pharmacology
Voronezh
O. G. Sharshova
Russian Federation
Sharshova Olga G., head of Dept of Endocrinology of Voronezh Children's Clinical Hospital
Voronezh
O. G. Galda
Russian Federation
Galda Olga G., 6th year student
Voronezh
M. V. Patritskaya
Russian Federation
Patritskaya Maria V., doctor of ultrasound diagnostics of Voronezh Children's Clinical Hospital
Voronezh
K. S. Niftaliev
Russian Federation
Niftaliev Kenan S., 5th year student
Voronezh
References
1. WHO European Regional Obesity Report 2022. Copenhagen: WHO Regional Offce for Europe; 2022. Licence: CC BY-NC-SA 3.0 IGO
2. Güngör N.K. Overweight and obesity in children and adolescents. Journal of clinical research in pediatric endocrinoljgy. 2014; 6(3): 129–43. https://doi.org/10.4274/Jcrpe.1471.
3. Chubarov T.V., Peterkova V.A., Batischeva G.A., Zhdanova O.A., Sharshova O.G., Artyushchenko A.I., Bessonova A.V. Characteristics of blood pressure level in children with different body weight. Obesity and metabolism. 2022;19(1):27–34. https://doi.org/10.14341/omet12721
4. Sinaiko A.R., Steinberger J., Moran A., Hong C.P., Prineas R.J., Jacobs D.R. Jr. Influence of insulin resistance and body mass index at age 13 on systolic blood pressure, triglycerides, and high-density lipoprotein cholesterol at age 19. Hypertension. 2006; 48(4): 730–6. https://doi.org/10.1161/01.HYP.0000237863.24000.50
5. Asma Deeb, Salima Attia, Samia Mahmoud, Ghada Elhaj, Abubaker Elfatih. Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children. Journal of Obesity. 2018; 8: 1–6. https://doi.org/10.1155/2018/8626818
6. Korsten-Reck U., Kromeyer-Hauschild K., Korsten K., Baumstark M.W., Dickhuth H., Berg A. Frequency of secondary dyslipidemia in obese children. Vascular Health and Risk Management. 2008; 4(5): 1089–1094. https://doi.org/10.2147/VHRM.S2928
7. Vos M.B., Abrams S.H., Barlow S.E. NASPGHAN Clinical Practice Guideline for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease in Children: Recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN). Journal of Pediatric Gastroenterology and Nutrition. 2017; 64(2): 319–334. https://doi.org/10.1097/MPG.0000000000001482
8. Zvyagin A.A., Fateeva N. Yu., Chubarov T.V., Zhdanova O.A. Steatohepatosis and steatohepatitis in overweight children: therapeutic methods. RMJ. 2022; 3: 9–12.
9. Peterkova V. A., Bezlepkina O. B., Bolotova N. V., Bogova E. A., Vasyukova O. V., Girsh Y.V., Kiyaev A.V., Kostrova I.B., Malievskiy O.A., Mikhailova E.G., Okorokov P.L., Petryaykina E.E., Taranushenko T.E., Khramova E.B. Clinical guidelines «Obesity in children». Problems of Endocrinology. 2021; 67(5): 67–83. (In Russ.) https://doi.org/10.14341/probl12802
10. Alimova I.L. Prospects of application in pediatric practice of the Federal clinical recommendations «Diagnosis and treatment of obesity in children and adolescents». Russian Bulletin of Perinatology and Pediatrics. 2015; 60(1): 66–70
11. Larentzakis A., Lygeros N. Artificial intelligence (AI) in medicine as a strategic valuable tool. Pan African Medical Journal. 2021; 38: 184. https://doi.org/10.11604/pamj.2021.38.184.28197.
12. González G., Ash S.Y., Vegas-Sánchez-Ferrero G., Onieva Onieva J., Rahaghi F.N., Ross J.C., Díaz A., San José Estépar R., Washko G.R.. Disease Staging and Prognosis in Smokers Using Deep Learning in Chest Computed Tomography. American Journal of Respiratory Critical Care Medicine. 2018; 197(2): 193–203. https://doi.org/10.1164/rccm.201705–0860OC
13. Weng S.F., Reps J., Kai J., Garibaldi J.M., Qureshi N. Can machine-learning improve cardiovascular risk prediction using routine clinical data? PLoS One. 2017; 12(4): e0174944. https://doi.org/10.1371/journal.pone.0174944.
14. Ells L.J., Rees K., Brown T. Interventions for treating children and adolescents with overweight and obesity: an overview of Cochrane reviews. International Journal Of Obesity. 2018; 42(11): 1823–1833. https://doi.org/10.1038/s41366–018–0230-y.
15. Pan L., Li X., Feng Y., Hong L. Psychological assessment of children and adolescents with obesity. Journal of International Medical Research. 2018; 46(1): 89–97. https://doi.org/10.1177/0300060517718733
16. Tsiros M.D., Sinn N., Coates A.M. Treatment of adolescent overweight and obesity.European Journal of Pediatrics. 2008; 167(1): 9–16. doi: 10.1007/s00431–007–0575-z
17. Wickham E. P. 3rd, DeBoer M. D. Evaluation and Treatment of Severe Obesity in Childhood. Clinical Pediatrics. 2015; 54(10): 929–40. https://doi.org/10.1177/0009922814565886
18. Kumar S., Kelly, A.S. Review of Childhood Obesity: From Epidemiology, Etiology, and Comorbidities to Clinical Assessment and Treatment. Mayo Clinic proceedings. 2017; 92(2): 251–265. https://doi.org/10.1016/j.mayocp.2016.09.01
19. Malhotra S., Czepiel K.S., Akam E.Y., Shaw A.Y., Sivasubramanian R., Seetharaman S., Stanford F.C. Bariatric surgery in the treatment of adolescent obesity: current perspectives in the United States. Expert Review of Endocrinology and Metabolism. 2021; 16(3): 123–134. https://doi.org/10.1080/17446651.2021.1914585
Review
For citations:
Chubarov T.V., Zhdanova O.A., Sharshova O.G., Galda O.G., Patritskaya M.V., Niftaliev K.S. Artifcial intelligence capabilities in evaluating effectiveness of non-medicinal treatment of obesity in children. Medical alphabet. 2022;1(18):20-24. (In Russ.) https://doi.org/10.33667/2078-5631-2022-18-20-24