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‘Otolithic’ dizziness

https://doi.org/10.33667/2078-5631-2022-10-40-44

Abstract

Labyrinth of the inner ear consists of two parts: semicircular canals and vestibulum. Vestibular disorders predominantly associated with vertigo – the feeling of moving of the surrounding objects and oscillopsia. However, vertigo is a result of the damage of ampullar receptors in semicircular canals and their connections with vestibular nuclei in brainstem. At the same time the dysfunction of otoliths system is much more mysterious and unpredictable. Elaboration of new methods of objective assessment of vestibular system provides a wonderful opportunity of the analysis of different components of the peripheral vestibular system including saccular and utricular parts. As a result of such analysis, it was demonstrated that otolithic dysfunction is a common consequence of the most frequent vestibular disorders like Meniere’s disease, benign paroxysmal positional vertigo and vestibular neuritis. It is not clear yet what is the clinical presentation of otolithic dysfunction and how otolithic dysfunction influence the prognosis of common vestibular disorders. It is unknown whether isolated otolithic dysfunction exists, for example in patients with unspecific disequilibrium or dizziness.

About the Authors

M. V. Zamergrad
Russian Medical Academy for Continuing Professional Education; City Clinical Hospital n.a. I. V. Davydovsky
Russian Federation

Zamergrad Maxim V., DM Sci (habil.), professor at Dept of Neurology with a course of reflexology and manual therapy, Russian Medical Academy for Continuing Professional Education

Moscow



S. S. Masueva
Russian Medical Academy for Continuing Professional Education; City Clinical Hospital n.a. I. V. Davydovsky
Russian Federation

Masueva Seda S., postgraduate student of Dept of Neurology with a course of reflexology and manual therapy, Russian Medical Academy for Continuing Professional Education; neurologist, City Clinical Hospital n.a. I. V. Davydovsky

Moscow



A. L. Guseva
Pirogov Russian National Research Medical University
Russian Federation

Guseva Aleksandra L., PhD Med, associate professor at Dept of Otorhinolaryngology, Faculty of Medicine

Moscow



S. P. Grachev
City Clinical Hospital n.a. I. V. Davydovsky; A. I. Evdokimov Moscow State University of Medicine and Dentistry
Russian Federation

Grachev Sergey P., DM Sci (habil.), professor at Dept of Cardiology

Moscow



References

1. Vestibulocochlear Nerve (CN VIII). In: Baehr M., Frotscher M., eds. Duus’ Topical Diagnosis in Neurology. Stuttgart, NY: Thieme; 2012: 175–194.

2. Cranial Nerve VIII (The Vestibulocochlear Nerve). In: Brazis P. W., Masdeu J.C., Biller J. Localization in Clinical Neurology. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2001.

3. Lindeman H.H. Anatomy of the Otolith Organs. Advances in Oto-Rhino-Laryngology. 1973; 20: 405–433. https://doi.org/10.1159/000393113

4. Wiest G., Baloh R. W. The Pioneering Work of Josef Breuer on the Vestibular System. Archives of Neurology. 2002; 59 (10): 1647. https://doi.org/10.1001/archneur.59.10.1647

5. Volkova L.M., Osipov L.V., Pavlov A.I. Evaluation of the statokinetic stability of students – future pilots of civil aviation. Health is the basis of human potential: problems and ways to solve them. 2016; 11 (1): 300–302. (In Russ.)

6. Sokolov Yu.A., Pantiukhov A.P., Korshuk M.V. Vestibulometry in the practice of medical flight examination: Teaching aid. Minsk BGMU; 2014. 60 (In Russ.)

7. Kingma H. Function tests of the otolith or statolith system. Current Opinion in Neurology. 2006; 19 (1): 21–25. https://doi.org/10.1097/01.wco.0000199021.48538.d9

8. Zwergal A., Rettinger N., Frenzel C., Dieterich M., Brandt T., Strupp M. A bucket of static vestibular function. Neurology. 2009; 72 (19): 1689–1692. https://doi.org/10.1212/wnl.0b013e3181a55ecf

9. De Pauw J., De Hertogh W., Mercelis R., Saeys W., Hallemans A., Michiels S., Truijen S., Cras P. Is perception of visual verticality intact in patients with idiopathic cervical dystonia? Acta Neurologica Belgica. 2017; 118 (1): 77–84. https://doi.org/10.1007/s13760–017–0853–0

10. Chetana N., Jayesh R. Subjective Visual Vertical in Various Vestibular Disorders by Using a Simple Bucket Test. Indian Journal of Otolaryngology and Head & Neck Surgery. 2014; 67 (2): 180–184. https://doi.org/10.1007/s12070–014–0760–0

11. Michelson P. L., McCaslin D.L., Jacobson G. P., Petrak M., English L., Hatton K. Assessment of Subjective Visual Vertical (SVV) Using the “Bucket Test” and the Virtual SVV System. American Journal of Audiology. 2018; 1: 1–11. https://doi.org/10.1044/2018_aja-17–0019

12. Schönfeld U., Helling K., Clarke A. H. Evidence of unilateral isolated utricular hypofunction. Acta Oto-Laryngologica. 2010; 130 (6): 702–707. https://doi.org/10.3109/00016480903397686

13. Dieterich M., Brandt T. Ocular torsion and tilt of subjective visual vertical are sensitive brainstem signs. Annals of Neurology. 1993; 33 (3): 292–299. https://doi.org/10.1002/ana.410330311

14. Zwergal A., Cnyrim C., Arbusow V., Glaser M., Fesl G., Brandt T., Strupp M. Unilateral INO is associated with ocular tilt reaction in pontomesencephalic lesions: INO plus. Neurology. 2008; 71 (8): 590–593. https://doi.org/10.1212/01.wnl.0000323814.72216.48

15. Rosengren S.M., Colebatch J.G. The Contributions of Vestibular Evoked Myogenic Potentials and Acoustic Vestibular Stimulation to Our Understanding of the Vestibular System. Frontiers in Neurology. 2018; 9: 1–17. https://doi.org/10.3389/fneur.2018.00481

16. Colebatch J. G., Halmagyi G. M. Vestibular evoked potentials in human neck muscles before and after unilateral vestibular deafferentation. Neurology. 1992; 42 (8): 1635–1636. https://doi.org/10.1212/wnl.42.8.1635

17. Rosengren S. M., McAngus Todd N. P., Colebatch J. G. Vestibular-evoked extraocular potentials produced by stimulation with bone-conducted sound. Clinical Neurophysiology. 2005; 116 (8): 1938–1948. https://doi.org/10.1016/j.clinph.2005.03.019

18. Murofushi T. Clinical application of vestibular evoked myogenic potential (VEMP). Auris Nasus Larynx. 2016; 43 (4): 367–376. https://doi.org/10.1016/j.anl.2015.12.006

19. Govender S., Dennis D.L., Colebatch J.G. Vestibular evoked myogenic potentials (VEMPs) evoked by air- and bone-conducted stimuli in vestibular neuritis. Clinical Neurophysiology. 2015; 126 (10): 2004–2013. https://doi.org/10.1016/j.clinph.2014.12.029

20. Kunel’skaya N.L., Baybakova E.V., Guseva A.L., Chugunova M.A., Manaenkova E.A. The importance of vestibular evoked myogenic potentials for the assessment of the otolith function in the patients presenting with benign paroxysmal positional vertigo. Bulletin of Otorhinolaryngology. 2017; 4: 5–8. (In Russ.).] http://doi.org/10.17116/otorino20178245–8

21. Isaradisaikul S., Navacharoen N., Hanprasertpong C., Kangsanarak J. Cervical Vestibular-Evoked Myogenic Potentials: Norms and Protocols. International Journal of Otolaryngology. 2012; 2012: 913515. https://doi.org/10.1155/2012/913515

22. Rosengren S.M., Govender S., Colebatch J.G. Ocular and cervical vestibular evoked myogenic potentials produced by air- and bone-conducted stimuli: Comparative properties and effects of age. Clinical Neurophysiology. 2011; 122 (11): 2282–2289. https://doi.org/10.1016/j.clinph.2011.04.001

23. Ferreira M. M., Ganança M. M., Caovilla H. H. Subjective visual vertical after treatment of benign paroxysmal positional vertigo. Braz J Otorhinolaryngol. 2017 Nov-Dec; 83 (6): 659–664. DOI: 10.1016/j.bjorl.2016.08.014. Epub 2016 Sep 28. PMID: 27746123.

24. Tarnutzer A. A., Bockisch C. J., Buffone E., Weber K. P. Vestibular mapping in patients with unilateral peripheral-vestibular deficits. Neurology. 2020 Dec 1; 95 (22): e2988–e3001. DOI: 10.1212/WNL.0000000000010812. Epub 2020 Sep 10. PMID: 32913014.

25. Kinoshita M., Iwasaki S., Fujimoto C., Inoue A., Egami N., Chihara Y., Ushio M., Yamasoba T. Ocular vestibular evoked myogenic potentials in response to air-conducted sound and bone-conducted vibration in vestibular schwannoma. Otol Neurotol. 2013 Sep; 34 (7): 1342–8. DOI: 10.1097/MAO.0b013e31828d6539. PMID: 23945552.

26. Chen L., Xu H., Wang W.Q., Zhang Q.Q., Lv Q.Y., Song X.C. Evaluation of the otolith function using c/o VEMPs in patients with Ménière's disease. J Otolaryngol Head Neck Surg. 2016 Jun 21; 45 (1): 39. DOI: 10.1186/s40463–016–0152–4. PMID: 27329136; PMCID: PMC4915077.

27. Okumura T., Imai T., Takimoto Y., Takeda N., Kitahara T., Uno A., Kamakura T., Osaki Y., Watanabe Y., Inohara H. Assessment of endolymphatic hydrops and otolith function in patients with Ménière's disease. Eur Arch Otorhinolaryngol. 2017 Mar; 274 (3): 1413–1421. DOI: 10.1007/s00405–016–4418–2. Epub 2016 Dec 10. PMID: 27942898.

28. Lopez-Escamez J.A., Carey J., Chung W.H., Goebel J.A., Magnusson M., Mandalà M., Newman-Toker D.E., Strupp M., Suzuki M., Trabalzini F., Bisdorff A. Criterios diagnósticos de enfermedad de Menière. Documento de consenso de la Bárány Society, la Japan Society for Equilibrium Research, la European Academy of Otology and Neurotology (EAONO), la American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) y la Korean Balance Society [Diagnostic criteria for Menière's disease. Consensus document of the Bárány Society, the Japan Society for Equilibrium Research, the European Academy of Otology and Neurotology (EAONO), the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) and the Korean Balance Society]. Acta Otorrinolaringol Esp. 2016 Jan-Feb; 67 (1): 1–7. Spanish. DOI: 10.1016/j.otorri.2015.05.005. Epub 2015 Aug 12. PMID: 26277738.

29. Fujimoto C., Suzuki S., Kinoshita M., Egami N., Sugasawa K., Iwasaki S. Clinical features of otolith organ-specific vestibular dysfunction. Clin Neurophysiol. 2018 Jan; 129 (1): 238–245. DOI: 10.1016/j.clinph.2017.11.006. Epub 2017 Nov 21. PMID: 29207275.

30. Curthoys I.S., Manzari L. Otolithic disease: clinical features and the role of vestibular evoked myogenic potentials. Semin Neurol. 2013 Jul; 33 (3): 231–7. DOI: 10.1055/s-0033–1354595. Epub 2013 Sep 21. PMID: 24057826.

31. Staab J.P., Eckhardt-Henn A., Horii A., Jacob R., Strupp M., Brandt T., Bronstein A. Diagnostic criteria for persistent postural-perceptual dizziness (PPPD): Consensus document of the committee for the Classification of Vestibular Disorders of the Bárány Society. J Vestib Res. 2017; 27 (4): 191–208. DOI: 10.3233/VES-170622. PMID: 29036855.

32. Lin C. M., Young Y. H. Identifying the affected branches of vestibular nerve in vestibular neuritis. Acta Otolaryngol. 2011 Sep; 131 (9): 921–8. DOI: 10.3109/00016489.2011.573504. Epub 2011 Apr 28. PMID: 21526905.

33. Clendaniel RA. On ‘The influence of otolith dysfunction…’ Murray et al. Phys ther. 2007; 87: 143–152. Phys Ther. 2007 Apr; 87 (4): 476–7; author reply 477. DOI: 10.2522/ptj.2007.87.4.476. PMID: 17400956.

34. Okuno T., Sando I. Localization, frequency, and severity of endolymphatic hydrops and the pathology of the labyrinthine membrane in Menière's disease. Ann Otol Rhinol Laryngol. 1987 Jul-Aug; 96 (4): 438–45. DOI: 10.1177/000348948709600418. PMID: 3619290.

35. Pender D.J. Membrane Stress in the Human Labyrinth and Meniere Disease: A Model Analysis. Int Arch Otorhinolaryngol. 2015 Oct; 19 (4): 336–42. DOI: 10.1055/s-0035–1549157. Epub 2015 Apr 7. PMID: 26491481; PMCID: PMC4593924.

36. Schuknecht H.F. Cupulolithiasis. Arch Otolaryngol. 1969 Dec; 90 (6): 765–78. DOI: 10.1001/archotol.1969.00770030767020. PMID: 5353084.

37. Park H.G., Lee J.H., Oh S.H., Park M.K., Suh M.W. Proposal on the Diagnostic Criteria of Definite Isolated Otolith Dysfunction. J Audiol Otol. 2019 Apr; 23 (2): 103–111. DOI: 10.7874/jao.2018.00374. Epub 2018 Dec 20. PMID: 30562878; PMCID: PMC6468282.

38. Suh M. W., Murofushi T. Response: Proposed Diagnostic Criteria for Definite Isolated Otolith Dysfunction. J Audiol Otol. 2021 Jan; 25 (1): 61–63. DOI: 10.7874/jao.2020.00661. Epub 2020 Dec 18. PMID: 33327704; PMCID: PMC 7835435.


Review

For citations:


Zamergrad M.V., Masueva S.S., Guseva A.L., Grachev S.P. ‘Otolithic’ dizziness. Medical alphabet. 2022;(10):40-44. (In Russ.) https://doi.org/10.33667/2078-5631-2022-10-40-44

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ISSN 2078-5631 (Print)
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