New opportunities in treatment of polycystic ovary syndrome
https://doi.org/10.33667/2078-5631-2022-4-27-30
Abstract
Aim. To analyze the efficiency of the use of inosit in the treatment of polycystic ovary syndrome (PCOS) in women of reproductive age.
Materials and methods. The prospective study included 80 patients aged 21 to 35 years with a diagnosis of PCOS. The main group consisted of 45 women who were prescribed inosit and lifestyle modification to correct symptoms of PCOS. The control group consisted of 35 women for whom was recommended only lifestyle modification. The condition of the patients was assessed at the beginning of therapy, after 3 and 6 months.
Results. During therapy, the patients of the main group showed a statistically significant effect of inosit on metabolic status: a decrease in fasting glucose and insulin levels, body mass index; hormonal status: a decrease in the level of androstenedione, testosterone, LH, normalization of the LH/FSH, a decrease in the clinical manifestations of hyperandrogenism; restored menstrual cycle with ovulation
Conclusions. The use of inosit along with a balanced diet and physical activity is an effective means for correcting clinical manifestations and improving the quality of life of women with PCOS.
About the Authors
A. B. Khuraseva
Kursk State Medical University
Russian Federation
Russian Federation
Khuraseva Anna B., MD, professor at Dept of Obstetrics and Gynecology of Institute of Continuing Education
Kursk
SPIN: 5905–9909,
Researcher ID: ААВ 6828–2020
K. S. Svyatchenko
Medical Centre ‘Zhivitsa’
Russian Federation
Russian Federation
Svyatchenko Ksenia S., obstetrician-gynecologist
Kursk
SPIN: 5905–9909бб,
Researcher ID: ААВ 6828–2020
I. N. Medvedev
Kursk State Medical University;
Medical Centre ‘Zhivitsa’
Russian Federation
Russian Federation
Medvedevа Irina N., PhD Med, associate professor at Dept of Obstetrics and Gynecology of Institute of Continuing Education1, obstetrician-gynecologist
Kursk
SPIN: 5905–9909б
Researcher ID: ААВ 6828–2020
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Review
For citations:
Khuraseva A.B., Svyatchenko K.S., Medvedev I.N. New opportunities in treatment of polycystic ovary syndrome. Medical alphabet. 2022;(4):27-30. (In Russ.) https://doi.org/10.33667/2078-5631-2022-4-27-30
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