Dynamics of level of class G antibodies to SARS-CoV-2 after new coronavirus infection COVID-19
https://doi.org/10.33667/2078-5631-2021-30-7-11
Abstract
The article presents the results of laboratory dynamic monitoring of the level of class G antibodies to SARS-CoV-2 in 160 patients within 3–10 months after the new coronavirus infection COVID-19. There was no decrease in the level of class G antibodies to SARS-CoV-2 to the threshold values and below in 91.2% of the examined patients.
About the Authors
S. S. Aleksanin
All-Russian Centre for Emergency and Radiation Medicine n. a. A. M. Nikiforov
Russian Federation
Russian Federation
Aleksanin Sergey S., DM Sci (habil.), professor, corresponding member of RAS, director
Saint Petersburg
N. A. Alkhutova
All-Russian Centre for Emergency and Radiation Medicine n. a. A. M. Nikiforov
Russian Federation
Russian Federation
Alkhutova Natalia A., PhD Bio, senior researcher of Laboratory of Serological Research and Allergy Diagnostics of the Laboratory Diagnostics Dept
Saint Petersburg
N. A. Kovyazina
All-Russian Centre for Emergency and Radiation Medicine n. a. A. M. Nikiforov
Russian Federation
Russian Federation
Kovyazina Nadezhda A., PhD Med, head of Laboratory of Serological Research and Allergy Diagnostics of the Laboratory Diagnostics Dept
Saint Petersburg
V. Yu. Rybnikov
All-Russian Centre for Emergency and Radiation Medicine n. a. A. M. Nikiforov
Russian Federation
Russian Federation
Rybnikov Viktor Yu., Dr. of Psychology (habil.), Dr. of Biological Sciences, professor, deputy director for research and academic affairs
Saint Petersburg
References
1. Popova A. Yu. Population immunity to the SARS-COV-2 virus among the population of St. Petersburg in the active phase of the COVID-19 epidemic. A. Yu. Popova [and others]. Problems of especially dangerous infections. 2020. No. 3. P. 124–130. DOI: 10.21055/0370–1069–2020–3–124–130.
2. Bao L, Deng W, Gao H, et al. Lack of reinfection in rhesus macaques infected with SARS-CoV-2. bioRxiv. Preprint posted May 1, 2020. DOI: 10.1101/2020.03.13.00–226.
3. Garcia LF. Immune response, inflammation, and the clinical spectrum of СОVID-19. Front Immunol. 2020; 11: 1441. DOI: 10.3389/fmmu.2020.01441.
4. Liu J, Guo J, Xu Q, Cai G, Chen D, Shen Y. Detection of IgG antibody during the follow-up in patients with COVID-19 infection. Crit Care. 2020; 24(1): 448. DOI: 10.1186/s13054–020–03138–4.
5. Maggi E, Canonica GW, Moretta L. Covid-19: Unanswered questions on immune response and pathogenesis. J Allergy Clin Immunol. 2020; 146 (1): 18–22. DOI: 10.1016/j.jaci.2020.05.001.
6. To KK, Tsang OT, Leung WS, et al. Temporal profles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. 2020; 20 (5): 565–574. DOI: 10.1016/S1473–3099(20)30196–1PubMedGoogleScholarCrossref.
7. Wölfel R, Corman VM, Guggemos W, et al. Virological assessment of hospitalized patients with COVID-2019. Nature. Published online April 1, 2020 DOI: 10.1038/s41586–020–2196-xPubMedGoogle Scholar.
8. Wu L-P, Wang N-C, Chang Y-H, et al. Duration of antibody responses after severe acute respiratory syndrome. Emerg Infect Dis. 2007; 13 (10): 1562–1564. DOI: 10.3201/eid1310.070576PubMedGoogleScholarCrossref.
9. Zhao J, Yuan Q, Wang H, et al. Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019 Clin Infect Dis. Published online March 28, 2020. DOI: 10.1093/cid/ciaa344PubMedGoogle Scholar.
Review
For citations:
Aleksanin S.S., Alkhutova N.A., Kovyazina N.A., Rybnikov V.Yu. Dynamics of level of class G antibodies to SARS-CoV-2 after new coronavirus infection COVID-19. Medical alphabet. 2021;1(30):7-11. (In Russ.) https://doi.org/10.33667/2078-5631-2021-30-7-11
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