Clinical phenotypes of lichen planus and transnosological psychosomatic comorbid states
Abstract
A sample of 120 patients with lichen planus presents the results of a prospective clinical study of phenotypic variants of dermatosis, in which itching acts as a leading nosogenic factor in the development of adjustment disorders of the depressive, neurotic, hypochondriac circle. The study of comorbid psychosomatic disorders associated with phenotypic manifestations of lichen planus is an urgent problem both in connection with severe forms of the disease, including excruciating itching, localization of rashes in open areas of the body, in the genital area, oral mucosa and the risk of malignant transformation of lesions, so and mediated violations of compliance at the stage of therapy and in the process of rehabilitation. The introduction of an integrated interdisciplinary approach into clinical practice contributes to the optimization of therapy for skin diseasе and an improvement in the quality of life of patients with comorbid psychosomatic pathology.
About the Authors
E. S. SnarskayaRussian Federation
Snarskayа Elena S., DM Sci (habil.), professor at Dept of Skin and Venereal Diseases.
Moscow
Scopus: 8714450500.
I. Yu. Dorozhenok
Russian Federation
Dorozhenok Igor Yu., PhD Med, associate professor at Dept of Psychiatry and Psychosomatics.
Moscow
Scopus: 35773056200.
M. V. Mikhailova
Russian Federation
Mikhailova Mariana V., post-graduate student of Dept of Skin and Venereal Diseases
Moscow
References
1. Dorozhenok I. Yu., Matyushenko E. N., Olisova O. Yu. Dysmorphophobia in dermatological practice. Russian Journal of Skin and Venereal Diseases. 2014; 1: 42–47.
2. Jalenques I, Lauron S, Almon S, Pereira B, D’Incan M, Rondepierre F. Prevalence and Odds of Signs of Depression and Anxiety in Patients with Lichen Planus: Systematic Review and Meta-analyses. Acta Derm Venereol. 2020; 100 (18): adv 00330. Published 2020 Nov 24. DOI: 10.2340/00015555–3660.
3. Koo J, Lee C. General Approach to Evaluating Psychodermatological Disorders. In: Koo J.Y.M., Lee C. S. (eds.). Psychocutaneous Medicine. New York: Marcel Dekker, Inc., 2003; 477: 1–12.
4. Smulevich A. B., Ivanov O. L., L’vov A.N., Dorozhenok I. Yu. Psychodermatological disorders. Dermatovenerology National Guide. Short edition. Moscow. GEOTAR-Medicine. 2013; 406–413.
5. Molochkov V. A., Prokof’ev A.A., Pereverzeva O. E. Bobrov M. A. Clinical features of the different forms of lichen ruber planus. Russian Journal of skin and venereal diseases. 2011; 1: 30–36.
6. Welz-Kubiak K, Reich A, Szepietowski J. Clinical Aspects of Itch in Lichen Planus. Acta Derm Venereol 2017; 97: 505–508. https://doi.org/10.2340/00015555–2563
7. Patrushev A.V., Samcov A.V., Suharev A.V., Minchenko A.A., Mamunov M.V. A new index for assessing the severity of lichen planus in clinical practice. Bulletin of Dermatology and Venereology. Volume: 96 (3): 2020. P. 27–33. DOI: 10.25208/vdv1145.
8. Adaskevich V. P. Diagnostic indexes in dermatology-Moscow: Panfilov Publishing House; Binom. Laboratory of knowledge. 2014. P. 16–18. ISBN978– 5–91839–043–6.
9. Rozzini R., Frisoni G. B., Ferrucci L., Barbisoni P., Sabatini T., Ranieri P., Guralnik J. M., Trabucchi M. Geriatric Index of Comorbidity: validation and comparison with other measures of comorbidity. Age Ageing. 2002; Jul; 31 (4): 277–285.
Review
For citations:
Snarskaya E.S., Dorozhenok I.Yu., Mikhailova M.V. Clinical phenotypes of lichen planus and transnosological psychosomatic comorbid states. Medical alphabet. 2021;(27):26-30. (In Russ.)