Development of sulfasalazine-associated drug-induced lupus erythematosus in patient with rheumatoid arthritis (clinical case)
https://doi.org/10.33667/2078-5631-2021-16-26-29
Abstract
Drug-induced lupus syndrome (DLS) is a rare adverse event with a variety of drugs. More than a hundred of drugs are known that can cause the development of DLS, and this list is growing as new drugs appear. Physicians of any specialty can face such complications of therapy and should be aware of this pathology. The article presents an analysis of a clinical case of DLS development against the background of long-term administration of sulfasalazine in a patient with a reliable diagnosis of rheumatoid arthritis, as well as a literature review, which includes data on the prevalence, drug groups, clinical manifestations, diagnosis and treatment of this pathology.
About the Authors
A. N. KovshikRussian Federation
Kovshik Anton N., rheumatologist at Dept of Rheumatology
E. P. Kiseleva
Russian Federation
Kiseleva Ekaterina P., rheumatologist at Dept of Rheumatology
N. G. Klyukvina
Russian Federation
Klyukvina Natalia G., DM Sci, leading researcher at Research Dept
of Rheumatology
G. V. Lukina
Russian Federation
Lukina Galina V., DM Sci, professor, head of Research Division of Rheumatology; lead researcher at Dept of Comorbid Infections and Monitoring the Safety of Drug Therapy
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Review
For citations:
Kovshik A.N., Kiseleva E.P., Klyukvina N.G., Lukina G.V. Development of sulfasalazine-associated drug-induced lupus erythematosus in patient with rheumatoid arthritis (clinical case). Medical alphabet. 2021;(16):26-29. (In Russ.) https://doi.org/10.33667/2078-5631-2021-16-26-29