Laboratory markers of premature aging and metabolic syndrome in liquidators of consequences of Chernobyl accident
https://doi.org/10.33667/2078-5631-2021-13-59-63
Abstract
In this paper, the metabolic syndrome (MS) is considered as a manifestation of an excessive adaptive response of the body, which underlies premature aging. It is relevant to search for new early markers of MS formation in LPA in the context of modern ideas about the role of universal mechanisms of adaptation and stress-induced premature aging in its pathogenesis. The data obtained by the authors allow us to consider the relative androgen deficiency as a predictor of the formation of MS in LPA. The results of the study demonstrate that the levels of triiodothyronine and DHEAS serve as early markers of the formation of MS, while the testosterone/estradiol ratio is a universal laboratory indicator of accelerated aging of the body and MS.
About the Authors
N. A. Alkhutova
All-Russian Centre for Emergency and Radiation Medicine n.a. A.M. Nikiforov
Russian Federation
Russian Federation
Alkhutova Natalia A., PhD Bio Sci, senior researcher at Laboratory of Serological Research and Allergy Diagnostics of the Laboratory Diagnostics Dept.
Saint Petersburg
N. А. Kovyazina
All-Russian Centre for Emergency and Radiation Medicine n.a. A.M. Nikiforov
Russian Federation
Russian Federation
Kovyazina Nadezhda A., PhD Med, head of Laboratory of Serological Research and Allergy Diagnostics of the Laboratory Diagnostics Dept.
Saint Petersburg
V. Yu. Rybnikov
All-Russian Centre for Emergency and Radiation Medicine n.a. A.M. Nikiforov
Russian Federation
Russian Federation
Rybnikov Viktor Yu., DM Sci, prof., deputy director for research and academic affairs.
Saint Petersburg
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Review
For citations:
Alkhutova N.A., Kovyazina N.А., Rybnikov V.Yu. Laboratory markers of premature aging and metabolic syndrome in liquidators of consequences of Chernobyl accident. Medical alphabet. 2021;(13):59-63. (In Russ.) https://doi.org/10.33667/2078-5631-2021-13-59-63
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