Behcet's disease (clinical case)
https://doi.org/10.33667/2078-5631-2020-31-34-37
Abstract
Behcet's disease (BD) is a rare systemic vasculitis, whfch affects vessels of different size. BD is diagnosed in the presence of recurrent aphthous stomatitis, combined with any two or more manifestations: genital ulcers, eye and skin damage and a positive pathergy testing, as well as the presence of positive HLA-B 51 test. This article describes the clinical case of a patient with Behcet's disease, who has a family aggregation of the disease, a wave-like course, and the gradual involvement of new systems. Authors have considered not only the development of clinical symptoms and the dynamics of the course of the disease, but also have presented algorithms for BD diagnosis and treatment in this patient, which had been based on the current national and international clinical recommendations focusing on the therapy impact on the prognosis in BD.
About the Authors
E. A. Bondarenko
Volgograd State Medical University
Russian Federation
Russian Federation
E. G. Cherkesova
Volgograd State Medical University
Russian Federation
Russian Federation
L. N. Shilova
Volgograd State Medical University
Russian Federation
Russian Federation
S. L. Bolotova
Volgograd State Medical University
Russian Federation
Russian Federation
References
1. Alekberova ZS, Lisitsyna TA. Behcet’s disease. In: Nasonov EL, editor. Revmatologiya: Klinicheskie rekomendatsii (Rheumatology. Russian clinical guidelines). Moscow: GEOTAR-Media; 2017. P. 210-28 (In Russ.)
2. Alekberova ZS. Bolezn' Bekhcheta: Monografiya [Behcet's Disease: Monograph. Moscow; 2007. 86 p. (In Russ.)
3. Klinicheskie rekomendatsii po bolezni Bekhcheta MZ RF (Clinical recommendations for Behcet's disease of the Ministry of Health of the Russian Federation). 2018. ID: KR 255. Available from: http://cr.rosminzdrav.ru (In Russ.)
4. Lisitsyna TA, Alek-berova ZS, Goloeva RG, Davydova GA. Behest’s disease: clinical manifestations, current principles of diagnosis and therapy. Nauchno Prakticheskaya Revma-tologiya = Rheumatology Science and Practice. 2019; 57 (5): 553-563 (In Russ.)
5. С. В. Моисеев, Н. М. Буланов, Е. А. Каровайкина, Н. Р. Носова, Е. А. Макаров, А. С. Зыкова, Е. И. Кузнецова, О. О. Бородин, Н. В. Никифорова, П. И. Новиков Современные представления о болезни Бехчета Клин. фармакол. тер., 2018, 27 (3), 58-66. Clinical Pharmacology and Therapy_2018.3.pdf
6. Criteria for diagnosis of Behest’s disease. International Study Group for Behest’s disease. Lancet. 1990. Vol. 335: 1078-1080.
7. Davatchi F, Assaad-Khalil S, Calamia KT, et al. The International Criteria for Behcet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatology Venereol 2014; 28 (3): 338-47.
8. Алекберова З. С., Измаилова Ф. И., Гусева И. А. и др. HLA-B 5/51-генотип: связь с клиническими проявлениями болезни Бехчета. Научно-практичекая ревматология 2015; 54 (4): 367-70.
9. Arber N, Klein T, Meiner Z, et al. Close association of HLA-B 51 and B 52 inIsraeli patients with Behcet’s syndrome. Ann Rheum Dis 1991; 50 (6): 351-3.
10. Zeidan MJ, Saadoun D, Garrido M, et al. Behcet's disease physiopathology: a contemporary review. Autoimmun Highlights. 2016 Dec; 7 (1): 4. DOI: 10.1007/s13317-016-0074-1.
11. Lisitsyna TA, Alekberova ZS, Goloeva RG. New guidelines for the management of patients with Behcet's disease/syndrome (EULAR, 2018). Nauchno-Prakticheskaya Revmatologiya Rheumatology Science and Practice. 2019; 57 (2): 133-41 (In Russ.). DOI: 10.14412/1995-4484-2019-133-141.
12. International Team for the Revision of the International Criteria for Behcet's Disease (ITR-ICBD). The International Criteria for Behcet's Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol. 2014; 28 (3): 338-47.
Review
For citations:
Bondarenko E.A., Cherkesova E.G., Shilova L.N., Bolotova S.L. Behcet's disease (clinical case). Medical alphabet. 2020;(31):34-37. (In Russ.) https://doi.org/10.33667/2078-5631-2020-31-34-37
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