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Surgery and metastases of stomach cancer in liver

https://doi.org/10.33667/2078-5631-2020-29-21-24

Abstract

Liver metastases of gastric cancer determine the poor prognosis. Until now The expediency of their surgical removal has been controversial. However, according to a number of studies, the removal of potentially operable isolated liver metastases allows a significant increase of overall and relapse-free survival in some cases. The review is dedicated to the analysis of prognostic factors that allow selecting patients for surgical removal of liver metastases of gastric cancer. The main criteria are: effective perioperative chemotherapy; stage under T4, N0, absence of lymphovascular invasion, absence of peritoneal dissemination, number less than 3, size up to 4 cm, localization of metastases in one lobe, low level of cancer markers CA 19-9 and CEA.

About the Authors

F. M. Dzhuraev
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation
Moscow.


S. L. Gutorov
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation
Moscow.


E. I. Borisova
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation
Moscow.


G. G. Khakimova
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation
Moscow.


References

1. Qiu MZ, Shi SM, Chen ZH, et al. Frequency and clinicopathological features of metastasis to liver, lung, bone, and brain from gastric cancer: A SEER-based study. Cancer Med 2018; 7: 3662-72.

2. Kinoshita, T., Kinoshita, T., Saiura, A., Esaki, M., Sakamoto, H., & Yamanaka, T. (2014). Multicentre analysis of long-term outcome after surgical resection for gastric cancer liver metastases. British Journal of Surgery, 102 (1), 102-107.

3. Tiberio G. A.M., Baiocchi G. L., Morgagni P., Marrelli D., Marchet A., Cipollari C., de Manzoni G. (2014). Gastric cancer and synchronous hepatic metastases: is it possible to recognize candidates to r0 resection? Annals of Surgical Oncology, 22 (2), 589-596.

4. Carmona-Bayonas A, Jimenez-Fonseca P, Echavarria I, Sanchez Canovas M et al. Surgery for metastases for esophageal-gastric cancer in the real world: Data from the AGAMENON national registry., Eur J Surg Oncol. 2018 Aug.

5. Sheraz R. Markar, Hugh Mackenzie, Sameh Mikhail et al. Surgical resection of hepatic metastases from gastric cancer: outcomes from national series in England. February 2016. The International Gastric Cancer Association and The Japanese Gastric Cancer Association 2016.

6. Li Z, Fan B, Shan F, Tang L, Bu Z, Wu A, et al. Gastrectomy in comprehensive treatment of advanced gastric cancer with synchronous liver metastasis: a prospectively comparative study. World J Surg Oncol. (2015) 13: 212.

7. Takemura N, Saiura A, Koga R, et al. Long-term outcomes after surgical resection for gastric cancer liver metastasis: an analysis of 64 macroscopically complete resections. Langenbecks Arch Surg 2012; 397: 951-957.

8. De Andrade JP, Mezhir JJ The critical role of peritoneal cytology in the staging of gastric cancer: an evidence-based review. J Surg Oncol. 2014 Sep; 110 (3): 291-7. Epub 2014 May 22.

9. Yamaguchi K, Yoshida K, Tanaka Y, et al. Conversion therapy for stage IV gastric cancer-the present and future. Transl Gastroenterol Hepatol 2016; 1: 50.

10. Yoshida K, Yamaguchi K, Okumura N, et al. Is conversion therapy possible in stage IV gastric cancer: the proposal of new biological categories of classification. Gastric Cancer 2016; 19: 329-38.


Review

For citations:


Dzhuraev F.M., Gutorov S.L., Borisova E.I., Khakimova G.G. Surgery and metastases of stomach cancer in liver. Medical alphabet. 2020;(29):21-24. (In Russ.) https://doi.org/10.33667/2078-5631-2020-29-21-24

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)