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Quantitative determination of drugs for therapy of COVID-19 in serum and plasma using liquid chromatography ― mass-spectrometry

https://doi.org/10.33667/2078-5631-2020-27-43-47

Abstract

There was developed a method for quantitation of the drugs which could be effective for COVID-19 treatment. Using tandem liquid mass-spectrometry it is possible to simultaneously quantify with high accuracy and precision up to 9 medicines in human plasma. This method could be used for new drug development as well as for clinical trials and therapeutic drug monitoring in real clinical practice.

About the Author

D. A. Farmakovsky
Shimadzu Europa GmbH
Russian Federation


Review

For citations:


Farmakovsky D.A. Quantitative determination of drugs for therapy of COVID-19 in serum and plasma using liquid chromatography ― mass-spectrometry. Medical alphabet. 2020;(27):43-47. (In Russ.) https://doi.org/10.33667/2078-5631-2020-27-43-47

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This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)