Mechanisms of liver damage in COVID-19
https://doi.org/10.33667/2078-5631-2020-19-39-46
Abstract
At the end of 2019, a new coronavirus (SARS-CoV-2) was discovered in China, causing the coronavirus infection COVID-19. The ongoing COVID-19 pandemic poses a major challenge to health systems around the world. There is still little information on how infection affects liver function and the significance of pre-existing liver disease as a risk factor for infection and severe COVID-19. In addition, some drugs used to treat the new coronavirus infection are hepatotoxic. In this article, we analyze data on the impact of COVID-19 on liver function, as well as on the course and outcome of COVID-19 in patients with liver disease, including hepatocellular carcinoma, or those on immunosuppressive therapy after liver transplantation.
About the Authors
T. V. Pinchuk
Russian National Research Medical University n.a. N.I. Pirogov
Russian Federation
Moscow
Russian Federation
Moscow
N. V. Orlova
Russian National Research Medical University n.a. N.I. Pirogov
Russian Federation
Moscow
Russian Federation
Moscow
T. G. Suranova
Academy of Postgraduate Education of the Federal Research and Clinical Centre for Specialized Medical Care and Medical Technologies
Russian Federation
Moscow
Russian Federation
Moscow
T. I. Bonkalo
Scientific and Research Institute of Healthcare Organization and Medical Management
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Pinchuk T.V., Orlova N.V., Suranova T.G., Bonkalo T.I. Mechanisms of liver damage in COVID-19. Medical alphabet. 2020;1(19):39-46. (In Russ.) https://doi.org/10.33667/2078-5631-2020-19-39-46
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