Preview

Medical alphabet

Advanced search

Psychogenic stress-dependent disorders of menstrual cycle: role of nonhormonal correction

Abstract

Menstrual disorders are widespread in the population, a significant part of them is associated with stress. However, stress is not identical simply to nervous tension, it is a nonspecific reaction to changes in conditions that require adaptation. Stress factors should be divided into physical, metabolic and psychological factors. Of particular importance are violations of the biological rhythms of the body, as well as psychological features of the relationship of patients with the mother. In general, with expressed stress, the reproductive function is inhibited. This effect is realized in several ways, in particular through transient hyperprolactinemia. Treatment of functional, stress-dependent hyperprolactinemia is carried out by plant dopaminomimetics. The use of Vitex agnus-castus drugs in such patients normalizes the secretion of prolactin and regulates the menstrual cycle.

About the Authors

I. V. Kuznetsova
First Moscow State Medical University n.a. I. M. Sechenov; Moscow Humanitarian University
Russian Federation


M. N. Burchakova
First Moscow State Medical University n.a. I. M. Sechenov; Moscow Humanitarian University
Russian Federation


D. I. Burchakov
First Moscow State Medical University n.a. I. M. Sechenov; Moscow Humanitarian University
Russian Federation


N. Kh. Khadzhieva
First Moscow State Medical University n.a. I. M. Sechenov; Moscow Humanitarian University
Russian Federation


G. G. Filippova
First Moscow State Medical University n.a. I. M. Sechenov; Moscow Humanitarian University
Russian Federation


References

1. Адильханова А.Х. Медико-социальные предпосылки становления репродуктивной системы у девочек-подростков из неблагополучных семей. Автореф. дисс.. канд. мед. наук. Санкт-Петербург, 2011.

2. Горелышев А., Кузнецова И. Менструальный цикл и энергетическая «политика» гипоталамуса. Эффективная фармакотерапия 2015; 5: 4-12.

3. Филлипова Г. Нарушения репродуктивной функции и ее связь с нарушениями в формировании материнской сферы. Журнал практического психолога 2003; 4-5: 83-109.

4. Кубасов Р. Функциональные изменения гипофизарно-гонадного и тиреоидного эндокринных звеньев в ответ на стрессовые факторы. Фундаментальные исследования 2014; 10: 1010-4.

5. Tworoger SS, Eliassen AH, Zhang X, Qian J, Sluss PM, Rosner BA, et al. A 20-year prospective study of plasma prolactin as a risk marker of breast cancer development. Cancer Res. 2013; 73:4810-9. doi:10.1158/0008-5472.CAN-13-0665.

6. McHale K, Tomaszewski JE, Puthiyaveettil R, LiVolsi VA, Clevenger C V. Altered expression of prolactin receptor-associated signaling proteins in human breast carcinoma. Mod. Pathol. 2008;21:565-71. doi:10.1038/modpathol.2008.7.

7. Freeman EW. Therapeutic management of premenstrual syndrome. Expert Opin. Pharmacother. 2010; 11: 2879-89. doi:10.1 517/14656566.2010.509344.

8. Biason TP, Goldberg TBL, Kurokawa CS, Moretto MR, Teixeira AS, Nunes HR de C. Low-dose combined oral contraceptive use is associated with lower bone mineral content variation in adolescents over a 1-year period. BMC Endocr. Disord. 2015; 15: doi:10.1186/s12902-015-0012-7.

9. Симоновская Х. Фитотерапия: зеленые перспективы. Интервью с председателем совета директоров компании «Бионорика» проф. Михаэлем Поппом. Status Praesens 2012; 5: 39-45.

10. Вуттке В., Зайдлова-Вуттке Д., Ярри Г., Артымук Н. Роль Витекса священного (Vitex agnus castus) в гинекологической эндокринологии. Гинекология 2014; 1: 4-7.

11. Wuttke W, Seidlova-Wuttke D, Jarry H, Artymuk N. Der Stelenwert des Monchspfeffer (Vitex agnus-castus). Zeitschrift Fur Phyther. 2010; 31: 294-8.

12. Артымук Н., Устинова Т., Власова В. Опыт применения Vitex Agnus Castus в комплексе лечения пациенток с синдромом поликистозных яичников и бесплодием. Российский вестник акушера-гинеколога 2011; 2: 65-8.

13. Цой Л. Лекарственная терапия диффузной мастопатии и ПМС. Онкология, гематология и радиология 2010; 3: 2-7.

14. Elsayed M. Agnucaston and Clomiphen Citrate in Infertile Patients with Polycystic Ovaries. J. Fertil. Vitr. IVF-Worldwide, Reprod. Med. Genitics Stem Cell Biol. 2013; 2: 33-40. doi:10.4172/2375-4508.1000108.

15. Khalilzadeh E, Vafaei Saiah G, Hasannejad H, Ghaderi A, Ghaderi S, Hamidian G, et al. Antinociceptive effects, acute toxicity and chemical composition of Vitex agnus-castus essential oil. Avicenna J. Phytomedicine n.d.; 5: 218-30.

16. Ma L, Lin S, Chen R, Zhang Y, Chen F, Wang X. Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women. Aust New Zeal. J. Obstet. Gynaecol. 2010; 50: 189-93. doi:10.1111/j.1479-828X.2010.01137.x.

17. Zamani M, Neghab N, Torabian S. Therapeutic effect of Vitex agnus castus in patients with premenstrual syndrome. Acta Med. Iran 2012; 50: 101-6.

18. van Die M, Burger H, Teede H, Bone K. Vitex agnus-castus Extracts for Female Reproductive Disorders: A Systematic Review of Clinical Trials. Planta Med. 2012; 79: 562-75. doi:10.1055/s-0032-1327831.

19. Arentz S, Abbott JA, Smith CA, Bensoussan A. Herbal medicine for the management of polycystic ovary syndrome (PCOS) and associated oligo/amenorrhoea and hyper-androgenism; a review of the laboratory evidence for effects with corroborative clinical findings. BMC Complement. Altern. Med. 2014; 14: 511. doi:10.1186/1472-6882-14-511.

20. Shahin AY, Mohammed SA. Adding the phytoestrogen Cimicifugae Racemosae to clomiphene induction cycles with timed intercourse in polycystic ovary syndrome improves cycle outcomes and pregnancy rates - a randomized trial. Gynecol. Endocrinol. 2014; 30: 505-10. doi:10.3109/095135 90.2014.895983.

21. Kamel HH. Role of phyto-oestrogens in ovulation induction in women with polycystic ovarian syndrome. Eur. J. Obstet. Gynecol. Reprod. Biol. 2013; 168: 60-3. doi:10.1016/j. ejogrb.2012.12.025.

22. Кузнецова И., Успенская Ю., Диль В., Гринева А. Использование растительных дофаминомиметиков у подростков и молодых женщин с нарушенным менструальным циклом. Акушерство и гинекология 2015; 10: 1-8.


Review

For citations:


Kuznetsova I.V., Burchakova M.N., Burchakov D.I., Khadzhieva N.Kh., Filippova G.G. Psychogenic stress-dependent disorders of menstrual cycle: role of nonhormonal correction. Medical alphabet. 2017;2(10):54-61. (In Russ.)

Views: 629


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)