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Neoadjuvant therapy for breast cancer. Value of residual disease

https://doi.org/10.33667/2078-5631-2020-20-30-33

Abstract

Drug treatment is an integral part of the complex approach for early and locally advanced breast cancer. The article considers the main goals and principles of neoadjuvant chemotherapy for different breast cancer subtypes, the relationship between complete pathomorpho-logical response and long-term results as well as approaches to the treatment of residual disease. A unified residual tumor assessment based on calculating the RCB-index after neoadjuvant chemotherapy allows to identify patient prognostic groups with different responses to treatment and, in turn, to plan additional therapy for them.

About the Authors

E. I. Kovalenko
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation
Moscow


E. V. Artamonova
Moscow
Russian Federation

Russian National Research Medical University n.a. N.I. Pirogov



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Review

For citations:


Kovalenko E.I., Artamonova E.V. Neoadjuvant therapy for breast cancer. Value of residual disease. Medical alphabet. 2020;(20):30-33. (In Russ.) https://doi.org/10.33667/2078-5631-2020-20-30-33

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)