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Modern medication of uterine myoma

Abstract

Myoma of the uterus is traditionally considered a surgical disease. Indeed, until recently the possibility of drug therapy for leiomyomas was extremely limited and included only preoperative preparation and prevention of the growth of small asymptomatic nodes. The breakthrough occurred after the introduction into clinical practice of selective modulators of progesterone receptors and the main representative of this group of drugs - ulipristal acetate. The article presents the results of preclinical trials, randomized controlled trials and the author s own experience in the treatment of uterine fibroids with the use of ulipristal acetate. The data accumulated so far allow us to state that the use of overground acetate is not only a good method of preoperative preparation of patients with uterine myoma, but also a worthy alternative to surgical treatment in patients planning fertility or refusing surgery.

About the Author

A. L. Tikhomirov
Moscow State Medical and Stomatological University n.a. A. I. Evdokimov
Russian Federation


References

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Review

For citations:


Tikhomirov A.L. Modern medication of uterine myoma. Medical alphabet. 2017;2(10):17-22. (In Russ.)

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)