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Influence of endogenous factors on glucose level in blood tests of patients of different age groups

https://doi.org/10.33667/2078-5631-2020-5-25-27

Abstract

Aim. Investigation of biochemical processes effect from cellular respiration on diagnostic information about level of glucose in venous blood.

Materials and Methods. We examined 115 blood samples in Vacutainer-type tubes with coagulation activator from patients aged 21 to 90 years. Patients were treated in ophthalmological, therapeutic and surgical departments of hospital. We evaluated correlation dependence of hematological factors effect on changes in glucose level during storage of samples.

Results. Three groups were ranked according to the size of each studied indicator. We have found effect of lymphocyte counts, eosinophils, platelets, as well as thrombocrit value, average platelet volume and relative width of platelet distribution by volume, age of patients on changes in glucose values for 24 and 48 hours of blood samples storage at a temperature of +4 °С.

Conclusion. Endogenous factors of blood samples is the important elements of pre-analytical phase in validating the results of clinical laboratory tests.

About the Authors

D. P. Piskunov
Saint-Petersburg State Pediatric Medical University; City Multidisciplinary Hospital No. 2
Russian Federation

Saint Petersburg



L. A. Danilova
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint Petersburg



L. V. Borisova
City Multidisciplinary Hospital No. 2
Russian Federation

Saint Petersburg



A. S. Pushkin
First Saint Petersburg State Medical University n. a. I. P. Pavlov; City Multidisciplinary Hospital No. 2
Russian Federation

Saint Petersburg



T. A. Akhmedov
First Saint Petersburg State Medical University n. a. I. P. Pavlov; City Multidisciplinary Hospital No. 2
Russian Federation

Saint Petersburg



V. L. Emanuel
First Saint Petersburg State Medical University n. a. I. P. Pavlov
Russian Federation

Saint Petersburg



References

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2. Linsey Porter, Nicole Toepfner, Kathleen R. Bashant, Jochen Guck, Margaret Ashcroft, Neda Farahi, Edwin R. Chilvers. Metabolic Profiling of Human Eosinophils. Frontiers in immunology. 2018; 9: 1404. doi.org/10.3389/fimmu.2018.01404.

3. M. Mibibula, K. M. Naseem, R. G. Sturmey. Glucose metabolism and metabolic flexibility in blood platelets. Journal of Thrombosis and Haemostasis. 2018; 16: 2300–14. doi.org/10.1111/jth.14274.

4. Rita Rastogi Kalyani, Josephine M. Egan. Diabetes and Altered Glucose Metabolism with Aging. Endocrinol Metab Clin North Am. 2013; 42 (2): 333–347. doi.org/10.1016/j.ecl.2013.02.010.


Review

For citations:


Piskunov D.P., Danilova L.A., Borisova L.V., Pushkin A.S., Akhmedov T.A., Emanuel V.L. Influence of endogenous factors on glucose level in blood tests of patients of different age groups. Medical alphabet. 2020;(5):25-27. (In Russ.) https://doi.org/10.33667/2078-5631-2020-5-25-27

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)