Preview

Medical alphabet

Advanced search

Left atrial strain in ischemic mitral regurgitation

Abstract

Aim. To evaluate left atrial global strain and strain rate and their correlation with mitral regurgitation severity in patients with chronic ischemic mitral regurgitation. Materials and methods. The analysis was performed in 118 patients with type Ilb ischemic mitral regurgitation according to Carpentier classification. Standard echocardiography and speckle tracking imaging were performed in order to assess left atrial global strain and strain rate. VIVID 7 Dimension (GE, Healthcare) ultrasound system and EchoPAC were used. Mitral valve (MV) geometry indices, mitral valve volumetric indices, left atrial volumes and left atrial ejection fraction were measured. Results. Left atrial strain values did not depend on mitral regurgitation severity. Left atrial global strain rate depended on mitral regur-gitation severity. The lowest values of left atrial global strain rate were presented in patients with grade 3 mitral regurgitation. Tenting of mitral leaflets correlated with left atrial global strain rate (r=-0,45; p=0,0003). Maximal left atrial volume correlated with the diameter of mitral annulus (r=0,56), coaptation depth (r=0,53), MV tenting area (r=0,56) and interpapillary muscle distance (r=0,51). Left atrial global strain and strain rate did not correlate with left atrial maximal volume and left atrial ejection fraction. Conclusions. MV tenting area, MV annular diameter, coaptation depth and coaptation heights correlate with left atrial maximal volume and global strain rate in patients with ischemic mitral regurgitation. Left atrial global strain rate depends on MR grade. Left atrial strain does not correlate with MR severity.

About the Authors

E. N. Pavlyukova
National Research Medical Centre, Russia Academy of Science
Russian Federation


T. Yu. Karetina
Cardiology Research Institute
Russian Federation


M. I. Gankin
Cardiology Research Institute
Russian Federation


V. A. Sakovich
Cardiology Research Institute
Russian Federation


References

1. Yu C. M., Fang F., Zhang Q., Yip G. W., Li C. M., Chan J. Y. Improvement of atrial function and atrial reverse remodeling after cardiac resynchronization therapy for heart future // J. Aim. Coll. Cardiol. -2007. -V.50. - N. 8. - P. 778-785.

2. Roska M., Popescu B. A., Beladan C. C., Calin A., Muraru D., Popa E. C. Left atrial dysfunction as a correlate of heart failure symptoms in hypertrophic cardiomyopathy //J. Am. Soc. Echocardiogr. - 2010. - V.23. - N.10. - P. 1090-1098.

3. Tsa W. S., Lee S. N., Lin C. C. Liu Y. W., Huang Y. Y., Li W. T. Association of left atrial strain and strain rate assessed by speckle tracking echocardiography with paroxysmal atrial fibrillation // Echocardiography. - 2009. - V. 26. - N. 10. - P. 1188-1194.

4. Popesku B. A., Macor F., Antonini-Canterin F., Giannuzzi P., Temporelli P. L., Bosimini E. GISSI-3 Echo Substudy Investigators. Left atrial remodeling after acute myocardial infarction (results of the GISSI-3 Echo Substudy) // Am. J. Cardiol. - 2004. - V. 93. -N. 9. - P.1156-1159.

5. Sun J. P., Yang Y., Guo R., Wang D., Lee A. P., Wang X. Y., et al. Left atrial regional phasic strain, strain rate and velocity by speckle-tracking echocardiography -normal values and effects of aging in a large group of normal subjects // Int. J. Cardiol. - 2003. - V. 168. - N. 4. - P. 3472-3479.

6. Lang R. M., Badano L. P., Mor-Avi V., Afilalo D., Armstrong A., Ernande L., Flachskampf F. A., Foster E., Goldstein S. A., Kuznetsova T., Lancellotti P., Muraru D., Picard M. H., Rietzschel E. R., Rudski L., Spencer K. T., Tsang W., Voigt J-U. Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging//European Heart Journal - Cardiovascular Imaging. - 2015. - V. 16. - P. 233-271.

7. Калинин А. О., Алехин М. Н., Бахс Г., Шипачов П. Н. Оценка деформации левого предсердия у больных артериальной гипертонией и аортальным стенозом с различной степенью гипертрофии левого желудочка/терапевтический архив 2012. - № 4. - С. 23-29. (Kalinin A., Alekhin M. N., Bachs G., Leinieks A., Kalninsh Sh., Schipachov P. Left atrial deformation in hypertensive patients with aortic stenosis and left ventricular hypertrophy of different severity // Therapeutic archive. - 2012. - N. 4. - P. 23-29.)

8. DcAndrea A., Caso P., Romano S. et al. Association between left atrial myocardial function and exercise capacity in patients with either idiopathic or ischemic dilated cardiomyopathy: A twodimensional speckle strain study // Int. J. Cardiol. - 2008. -V.10. - P. 26-32.

9. DcAndrea A., De Corato G., Scarafile R. et al. Left atrial myocardial function in either physiological or pathological left ventricular hypertrophy: a twodimensional speckle strain study // Br. J. Sports. Med. - 2008. - V. 42. - P. 696-702.

10. DcAndrea A., Caso P., Romano S. et al. Different effects of cardiac resynchronization therapy on left atrial function in patients with either idiopathic or ischaemic dilated cardiomyopathy: a twodimensional speckle strain study //Eur. Heart J. - 2007. - V. 28. - P. 2738-2748.

11. Кардиология: национальное руководство / под ред. Ю. Н. Беленкова, Р. Г. Оганова. - М.: ГЭОТАР, Медицина, 2008. - 1232 с. (Cardiology: national leadership / under red. Yu. N. Belenkov, RG Oganov. - M.: GEOTAR, Medicine, 2008. - 1232р.)

12. Шиллер Н. Б., Осипов М. А. Клиническая эхокардиография. Изд. 2-е. М., Практика. - 2005. - 344с. (Schiller N. B., Osipov M. A. Clinical Echocardiography. Ed. 2nd. M., 2005. Praktika. - 344 р).

13. Nagueh F., Appleton G. P., Gillebert T. C., Marino P., Oh J. K., Smiseth O. A., Waggoner A. D., Flachskampf F. A., Pellikka P. A., A. Evangelista. Recommendations for the Evaluationof ventricular Diastolic Function by Echocardiography // J. Am. Soc. Echocardiog. - 2009. - V. 22. - N. 2. - P. 105-123.

14. Бузиашвили Ю. И., Кокшенова И. В., Асымбекова Э. У., Тугеева Э. Ф., Голубев Е. П., Мацкеплишвили С. Т. Ишемическая митральная регургита-ция: механизмы разивтия и прогрессирования. Актуальные вопросы лечебной тактики. М.: НЦССХ им А. Н. Бакулева РАМН; 2014.196 с. (Buziashvili Y. I., Kokshenova I. V., Asymbekova E. W., Tugeeva E. F., Golubev E. P., Matskeplishvili S. T. Ischemic mitral regurgitation: mechanisms and progression. Actual questions of medical tactics. M.: AN NTSSSH them Bakuleva RAMS; 2014.196p.)

15. Fattouch K., Lancellotti P., Angeli-ni G. D. Secondary Mitral Regurgitation. Springer-Verlag London 2015. 206 p.

16. Lancellotti P.1, Moura L., Pierard L. A., Agricola E., Popescu B. A., Tribouilloy C., Hagendorff A., Monin J. L., Badano L., Zamorano J. L.; European Association of Echocardiography. European Association of Echocardiography recommendations for the assessment of valvular regurgitation. Part 2: mitral and tricuspid regurgitation (native valve disease) // European Journal of Echocardiography. - 2010. - V.11. - N. 4. - P. 307-332.

17. Райдинг Э. Эхокардиография: практическое руководство. М., МЕДпресс-информ. 2010, 277 c. (Riding E. Echocardiography: A Practical Guide. M. MEDpressinform. 2010, 277 p).

18. Reisner S. A., Lysyansky P., Agmon Y. et al. Global longitudinal Strain: a novel index of left ventricular systolic function // J. Am. Soc. Echocardiogr. - 2004. - Vol. 17. - P. 630-633

19. Inaba Y., Yuda S., Kibayashi N., Hashimoto A., Uno K., Nakata T., Tsuchihashi K., Miura T., Ura N., Shimamoto K. Strain RateImaging fotr Noninvasive Functional Quantification of the Left Atrium: Comparative Studies in Controls and Patients With Atrial Finrillation // J. Am. Soc. Echocardiogr. - 2005. - V. 18. - P. 729-736.

20. Motoki H., Dahiya A., Bhargava M., Wazni O., Saliba W. I., Marwick T. H., Klien A. L. Assessment of left Atrial Mechanics in Patients With Atrial Fibrillation; Compaarison between Two-Dimensional Speckle -Based Strain and Velocity vector maging//J. Am. Soc. Echocardiogr. - 2012. - V. 25. -N. 4. - P. 428-435.

21. Матановская Т. В., Туев А. В., Орехова Е. Н., Суханов С. Г. Оценка механической функции левого предсердия у здоровых взрослых // Методы диагностики и технологии. - 2014. - Т. 31. - №. 1. - С. 64-72. (Matanovskaya T. V., Tuev A. V., Orekhova E. N., Sukhanov S. G. Assessment of left atrium mechanical function in healthy adults // Diagnostic methods and techniques. - 2012. -№ 4. - Р.23-29.)


Review

For citations:


Pavlyukova E.N., Karetina T.Yu., Gankin M.I., Sakovich V.A. Left atrial strain in ischemic mitral regurgitation. Medical alphabet. 2017;1(14):32-36. (In Russ.)

Views: 372


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)