Extracellular DNA in oncological and other diseases related to apoptosis disorder
https://doi.org/10.33667/2078-5631-2019-3-28(403)-47-51
Abstract
Results are presented of own studies of extracellular DNA (exDNA) in experiment of animals with transplanted ovarian cancer, after exposure to ionizing radiation, with benign prostatic hyperplasia, clinical studies in patients with chronic obstructive pulmonary disease and with acute disorders of cerebral circulation. The possibilities of exDNA determination for minimally invasive diagnostics in oncological diseases, formation of risk groups, monitoring of diseases, studying mechanisms of action and individual sensitivity to drug therapy are considered.
About the Authors
I. N. Vasilyeva
National Medical Research Centre of Oncology n.a. N.N. Petrov
Russian Federation
Saint Petersburg
Russian Federation
Saint Petersburg
V. G. Bespalov
National Medical Research Centre of Oncology n.a. N.N. Petrov;
ITMO University
Russian Federation
Saint Petersburg
Russian Federation
Saint Petersburg
A. L. Semyonov
National Medical Research Centre of Oncology n.a. N.N. Petrov
Russian Federation
Saint Petersburg
Russian Federation
Saint Petersburg
G. V. Tochilnikov
National Medical Research Centre of Oncology n.a. N.N. Petrov
Russian Federation
Saint Petersburg
Russian Federation
Saint Petersburg
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Review
For citations:
Vasilyeva I.N., Bespalov V.G., Semyonov A.L., Tochilnikov G.V. Extracellular DNA in oncological and other diseases related to apoptosis disorder. Medical alphabet. 2019;3(28):47-51. (In Russ.) https://doi.org/10.33667/2078-5631-2019-3-28(403)-47-51
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