Placental and serum production of cytokines and relaxin in pregnant women with diabetes mellitus
https://doi.org/10.33667/2078-5631-2019-3-25(400)-43-45
Abstract
Objective of research was to study the production of serum and placental cytokines and relaxin in women with a physiological pregnancy (45) and complicated by type I diabetes mellitus (42). The research material was the placenta and serum of pregnant women, in which determined the level of cytokines TNF-α, TGF-β, IL-1β and relaxin. It has been shown that the cytokine-producing function of the placenta plays an important role in the development of that organ, and systemic production of cytokines and relaxin is of key importance in the development of endothelial dysfunction syndrome. Early diagnosis of complications in pregnant women with type 1 diabetes will make it possible to start etiopathogenetic therapy in a timely manner and makes it possible to perform adequate obstetric tactics of labor.
About the Authors
I. I. Krukier
Rostov State Medical University
Russian Federation
Rostov-on-Don
Russian Federation
Rostov-on-Don
V. V. Avrutskaya
Rostov State Medical University
Russian Federation
Rostov-on-Don
Russian Federation
Rostov-on-Don
A. A. Grigoriants
Stavropol State Medical University
Russian Federation
Stavropol
Russian Federation
Stavropol
A. S. Degtyaryova
Rostov State Medical University
Russian Federation
Rostov-on-Don
Russian Federation
Rostov-on-Don
A. A. Nikashina
Rostov State Medical University
Russian Federation
Rostov-on-Don
Russian Federation
Rostov-on-Don
A. V. Rozhkov
Clinic No. 1 of the Federal Customs Service of Russia
Russian Federation
Rostov-on-Don
Russian Federation
Rostov-on-Don
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Review
For citations:
Krukier I.I., Avrutskaya V.V., Grigoriants A.A., Degtyaryova A.S., Nikashina A.A., Rozhkov A.V. Placental and serum production of cytokines and relaxin in pregnant women with diabetes mellitus. Medical alphabet. 2019;3(25):43-45. (In Russ.) https://doi.org/10.33667/2078-5631-2019-3-25(400)-43-45
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