Factors of increasing perioperative blood loss in cardiac surgery
Abstract
Seventy three patients who underwent on-pump CABG surgery were examined. in 33 patients (group 1), perioperative blood loss of 10 or more ml/kg was noted, in other cases (n = 40, group 2) it was less than 10 ml/kg. in group 1, compared with group 2, the antiplatelet effect of aspirin measured by optical transmission aggregometry (570 ± 77; 620 ± 55 ARU; p = 0.0009), the total dosages of heparin (594 ± 110; 520 ± 54 U/ kg; p = 0.002) and protamine sulfate (4.7 ± 1.0; 3.9 ± 0.5 mg/ kg; p = 0.0005). Thus, the antiplatelet effect of aspirin administered before the operation, and the total dose of heparin, despite the calculated neutralization with protamine sulfate, are significant risk factors for an increase in perioperative blood loss during CABG-surgery.
Keywords
About the Authors
N. V. Guseva
City Clinical Hospital n.a. S. S. Yudin
Russian Federation
Russian Federation
M. S. Akulenko
City Clinical Hospital n.a. S. S. Yudin
Russian Federation
Russian Federation
A. V. Tikhonov
City Clinical Hospital n.a. S. S. Yudin
Russian Federation
Russian Federation
A. A. Dvoryadkin
City Clinical Hospital n.a. S. S. Yudin
Russian Federation
Russian Federation
E. A. Plemyannikova
City Clinical Hospital n.a. S. S. Yudin
Russian Federation
Russian Federation
L. A. Krichevsky
City Clinical Hospital n.a. S. S. Yudin
Russian Federation
Russian Federation
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For citations:
Guseva N.V., Akulenko M.S., Tikhonov A.V., Dvoryadkin A.A., Plemyannikova E.A., Krichevsky L.A. Factors of increasing perioperative blood loss in cardiac surgery. Medical alphabet. 2018;4(38):22-25. (In Russ.)
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