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Goal-directed fluid resuscitation in critically ill patients. Literature review

Abstract

An important part of treating critically ill patients is infusion therapy that is aimed at cardiac output increase, tissue perfusion improvement and organ failure prevention. Herewith, recent research data show that more than 20 % of infusion therapy cases are associated with problems related with its irrational application. Excessive rehydration causes tissue edema, electrolyte disorders, development of acute respiratory distress syndrome and kidney injury. in case of sepsis, starting from the second day after intensive care unit (iCU) admission, the positive cumulative fluid balance is accompanied by increased duration of mechanical ventilation, longer iCU stay and increased mortality. Nowadays, much attention is paid not only to the adequate filling of vascular capacity and interstitial space but also to the in-time dehydration or deresuscitation under control of invasive monitoring of hemodynamics.

About the Authors

N. O. Khromacheva
Northern State Medical University; First City Clinical Hospital n.a. E. E. Volosevich
Russian Federation


A. A. Kuzmenko
Northern State Medical University; Regional Hospital, Toksovo
Russian Federation


E. V. Fot
Northern State Medical University; First City Clinical Hospital n.a. E. E. Volosevich
Russian Federation


V. V. Kuzkov
Northern State Medical University; First City Clinical Hospital n.a. E. E. Volosevich
Russian Federation


M. Y. Kirov
Northern State Medical University; First City Clinical Hospital n.a. E. E. Volosevich
Russian Federation


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Review

For citations:


Khromacheva N.O., Kuzmenko A.A., Fot E.V., Kuzkov V.V., Kirov M.Y. Goal-directed fluid resuscitation in critically ill patients. Literature review. Medical alphabet. 2018;4(38):10-16. (In Russ.)

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