NSAID-gastropathyin polyclinical practice
Abstract
NSAID-gastropathy is one of the most relevant medical and social problems of health care, which is at the crossroads of many therapeutic areas. Nowadays acetylsalicylic acid is one of the most widely used drugs in the world. According to the international cardiological and gastroenterological associations, the use of ASA in a dose of 75 mg leads to an increase in side effects from the gastrointestinal tract by 2-4 times. This fact determines the importance of the management of such patients by the doctors of the district physicians, as well as the prevention of NSAIDs-gastropathy in general.
About the Authors
M. A. Osadchuk
First Moscow State Medical University n.a. I. M. Sechenov
Russian Federation
Russian Federation
N. V. Kireeva
First Moscow State Medical University n.a. I. M. Sechenov
Russian Federation
Russian Federation
A. E. Lazareva
First Moscow State Medical University n.a. I. M. Sechenov
Russian Federation
Russian Federation
D. A. Shorina
First Moscow State Medical University n.a. I. M. Sechenov
Russian Federation
Russian Federation
A. A. Hudarova
First Moscow State Medical University n.a. I. M. Sechenov
Russian Federation
Russian Federation
E. D. Mironova
First Moscow State Medical University n.a. I. M. Sechenov
Russian Federation
Russian Federation
References
1. Каратеев А. Е., Насонов Е. Л., Яхно Н. Н. и др. Клинические рекомендации «Рациональное применение нестероидных противовоспалительных препаратов (НПВП) в клинической практике». // Современная ревматология. 2015; 9 (1): 4-23.
2. Bhatt D.L, Scheiman J., Abraham N.S. et al. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. // J Am Coll Cardiol. 2008; 52: 1502-1517.
3. А. А. Свистунов, М. А. Осадчук, Н. В. Киреева, А. А. Хударова, Е. Е. Ачкасов НПВП-индуцированная энтеропатия: современное состояние проблемы. Тера певтический архив. 2018; 08: 95-100. doi. org/10.26442/terarkh201890895-100.
4. Хударова А., Осадчук М. НПВП-гастропатии: прогнозирование течения и исходов // Врач.- 2018; 29 (5): 17-23. doi: 10.29296/25877305-2018-05-04.
5. Garcia Rodriguez L. A., Martin-Pérez M., Hennekens C. H., Rothwell P. M., Lanas A. Bleeding risk with long-term low-dose aspirin: a systematic review of observational studies. PLoS One. 2016; 11: e0160046.
6. Chi T. Y., Zhu H. M., Zhang M. Risk factors associated with nonsteroidal anti-inflammatory drugs (NSAIDs)-induced gastrointestinal bleeding resulting on people over 60 years old in Beijing. Medicine (Baltimore). 2018 May; 97 (18): e0665. doi: 10.1097/ MD.0000000000010665.
7. Lanza F. L., Chan F. K., Quigley E. M. Practice Parameters Committee of the American College of Gastroenterology. Guidelines for prevention of NSAID-related ulcer complications. // Am J Gastroenterol. 2009; 104: 728-738.
8. Lavie C. J., Howden CW, Scheiman J, Tursi J. Upper Gastrointestinal Toxicity Associated With Long-Term Aspirin Therapy: Consequences and Prevention. // Curr Probl Cardiol. 2017 May; 42 (5): 146-164. doi: 10.1016/j.cpcardiol.2017.01.006. Epub 2017 Feb 1.
9. Malfertheiner P., Megraud F., O'Morain C. A. Gisbert J. P., Kuipers E. J., Axon A. T., Bazzoli F., Gasbarrini A., Atherton J., Graham D. Y., Hunt R., Moayyedi P., Rokkas T.1, Rugge M., Selgrad M., Suerbaum S., Sugano K., El-Omar E.M.20; Management of Helicobacter pylori infection - the Maastricht V/Florence Consensus Report Gut. 2017 Jan; 66 (1): 6-30. doi: 10.1136/ gutjnl-2016-312288. Epub 2016 Oct 5.
10. Moore A., Makinson G., Li C. Patient-level pooled analysis of adjudicated gastrointestinal outcomes in celecoxib clinical trials: meta-analysis of 51,000 patients enrolled in 52 randomized trials. // Arthritis Res Ther 2013; 15 (1): 6.
11. Venerino M., Malfertheiner P. Interaction of Helicobacter pylori infection and Non-steroidal Anti-inflammatory Drugs in Gastric and Duodenal Ulcers // Helicobacter. 2010. Vol. 15. P. 239-250.
12. Szabó I. L., Matics R., Hegyi P., Garami A., Illés A., Sarlós P., Bajor J., Szucs A., Mosztbacher D., Marta K., Szemes K., Cseko K., Kovari B., Rumbus Z., Vincze A. PPIs Prevent Aspirin-Induced Gastrointestinal Bleeding Better than H2RAs. A Systematic Review and Meta-analysis. J Gastrointestin Liver Dis. 2017 Dec; 26 (4): 395-402. doi: 10.15403/ jgld.2014.1121.264.hra.
Review
For citations:
Osadchuk M.A., Kireeva N.V., Lazareva A.E., Shorina D.A., Hudarova A.A., Mironova E.D. NSAID-gastropathyin polyclinical practice. Medical alphabet. 2018;3(30):33-36. (In Russ.)
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