Frequency of virulent and moderate endogenous bacteriophage detection in patients with thermal trauma
Abstract
The study of the presence of endogenous bacteriophages in burned patients with bacteremia has been made. The data on the frequency of virulence and moderate phage are presented. It was been established that sepsis and fatal outcomes in patients with endogenous phages, regardless of the form of interaction with the microbial cell, were less common than in patients without phages.
About the Authors
E. B. Lazareva
Research Institute of Emergency Care n.a. N. V Sklifosovsky
Russian Federation
Russian Federation
E. D. Menshikova
Research Institute of Emergency Care n.a. N. V Sklifosovsky
Russian Federation
Russian Federation
N. V. Evdokimova
Research Institute of Emergency Care n.a. N. V Sklifosovsky
Russian Federation
Russian Federation
T. V. Chernenkaya
Research Institute of Emergency Care n.a. N. V Sklifosovsky
Russian Federation
Russian Federation
T. G. Spiridonova
Research Institute of Emergency Care n.a. N. V Sklifosovsky
Russian Federation
Russian Federation
E. A. Zhirkova
Research Institute of Emergency Care n.a. N. V Sklifosovsky
Russian Federation
Russian Federation
T. L. Zhilenkov
MikroMir Co
Russian Federation
Russian Federation
References
1. Шендеров Б. А. Медицинская микробная экология и функциональное питание. Т. 1: Микрофлора человека и животных и ее функции.-М.: ГРАНТЪ, 1998. - 288 с.
2. Luckey T. D. Overview of gastrointestinal microecology. // Nahrung.- 1987.- Vol. 31, N5-6.- P. 359-64.
3. Бактериофаги: биология и практическое применение / под. ред. Э. Каттер, А. Сулаквелидзе.- М.: Научный мир, 2012.- 638 с.
4. Stern A., Mick E., Tirosh I., et al. CRISPR targeting reveals a reservoir of common phages associated with the human gut microbiome. // Genome Res.- 2012.- Vol. 22, N 10.- P. 985-94.
5. Górski A., Weber-Dabrowska B. The potential role of endogenous bacteriophages in controlling invading pathogens. і і Cell Mol Life Sci. - 2005.- Vol. 62, N 5.- P. 511-9.
6. Реброва О. Ю. Статистический анализ медицинских данных. Применение пакета прикладных программ STATISTICA.- М.: Медиа Сфера, 2003.- 312 с.
7. Марченко Б. И. Здоровье на популяционном уровне: статистические методы исследования: руководство для врачей.- Таганрог: Сфинкс, 1997. - 432 с.
8. Mills S., Shanahan F., Stanton C., et al. Movers and shakers: influence of bacteriophages in shaping the mammalian gut microbiota. // Gut Microbes.-2013.-Vol. 4, N 1.- P. 4-16.
9. Letarov A., KulikovE. The bacteriophages in human- and animal body-associated microbial communities. // J Appl Microbi ol.- 2009.- Vol. 107, N 1.- P. 1-13.
Review
For citations:
Lazareva E.B., Menshikova E.D., Evdokimova N.V., Chernenkaya T.V., Spiridonova T.G., Zhirkova E.A., Zhilenkov T.L. Frequency of virulent and moderate endogenous bacteriophage detection in patients with thermal trauma. Medical alphabet. 2018;3(28):55-58. (In Russ.)
Views:
275
Email this article 