Current course of cryptosporidiosis, it's diagnosis and treatment

Abstract

Aim of research. To identify the features of the course of cryptosporidiosis, to improve methods of laboratory diagnosis and treatment. Patients and methods: 266 patients of the infectious hospital were observed. To find out oocysts of Cryptosporidia were used: classical microscopic method of modified coloration of fecal swabs according to Tsiol-Nielsenus with the following study in immersion microscopy; the qualitative determination of antigens by the RINA QUICK Cryptosporidium pavrum immunochromatographic test; Immunological analysis (Cryptosporidium Antigen (Stool) ELISA). The intestinal microfiora was studied for dysbacteriosis (Standard for managing patients with intestinal dysbacteriosis (N. M. Gracheva et al., 2004). In complex treatment of 33 patients was used sporobacterin 2 ml twice a day for 10 days. Results. In 26.3 % of patients with infectious diseases, cryptosporidia was found. In 94.3 % of cases, the latent flow was diagnosed, and in 5.7% the intestinal form. In acute period all patients had dysbacteriosis of the intestine of 2-3 degrees. After treatment, there was a positive dynamics in the microbiocenosis of the intestine, which manifested as an increase in the number of patients with minor disturbances in the microfiora (DI 1 25.7 %). Conclusion. When 266 patients were examined, in 26.3 % of cases, oocysts cryptosporidia were found. In the clinical picture, intestinal forms with a latent course dominated against the background of pronounced dysbiotic disorders (DI2-DI3). The inclusion of sporobakterin in the complex therapy of patients had a positive clinical and microbiological effect.