Diagnosis of airway obstruction of moderate severity by the method of pulsed oscillometry

The impulse oscillometry (lOS) is noninvasive method of studying of lung mechanical properties based on analysis of sound oscillations reflected by airways of the patients. lOS allows to measure respiratory impedance (Zrs) and its components: resistance (Rrs) and reactance (Xrs). The lOS parameters are measured at quiet breath during 30-60 s and do not require an active cooperation of the patient. The aim of our study was to research the opportunities of lOS for diagnostics of moderate obstructive ventilatory disorders. We analyzed the lOS and PFTs (spirometry, body plethysmography, diffusion test) data of 80 patients which were divided to two groups: 30 patients with moderate obstruction (FEV₁ in the range 60-70%pred, 27 (90%) males and 3 (10%) females, mean age 57 ± 15 years (21-78 years)), 50 patients with mild obstruction (FEVj more than 70 %pred, 38 (76 %) males and 12 (24 %) females, mean age 54 ± 16 years (19-82 years)). Conclusions: 1) 57 % of patients with moderate obstruction diagnosed with spirometry had obstructive disorders in accordance with the traditional lOS interpretation algorithm. 2) The change in AX (areas under the Xrs-curve in the frequency range from 5 Hz to f_res) was more often detected in patients with moderate obstruction than with mild obstruction (80 % and 64 %, respectively), as well as changes in the absolute frequency dependence (Rrs5-Rrs20) (76 % and 54 %, respectively). This indicates the possibility of including these parameters to the algorithm of the lOS interpretation. 3) The severity of airway obstruction lOS-diagnosed does not always coincide with the severity of the disorders determined by spirometry: 37 % of patients with moderate obstruction, spirometry-diagnosed, had more severe obstruction determined by lOS.

the impulse oscillometry, moderate airways obstruction, pulmonary function tests

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