Preview

Medical alphabet

Advanced search

Antibiotic susceptibility of methicillin-resistant Staphylococcus spp., isolated from emergency hospital patients

Abstract

Throughout the world, methicillin-resistant Staphylococcus spp. are the most commonly identified causative infective agents in patients of emergency hospitals. It has been studied the frequency of their detection in our emergency hospital in year 2016. Thus, the detection rate of methicillin-resistant Staphylococcus aureus (MRSA) was 63,4 % and coagulase-negative Staphylococcus spp. (MRCNS) was 81 %. All the strains were sensitive to linezolid. In addition, 71,1 % of MRSA and 100 % of MRCNS were sensitive to vancomycin; 71,4 % of MRSA and 83,3 % of MRCNS were sensitive to daptomycin; 37,1 % of MRSA were sensitive to ceftaroline.

About the Authors

T. V. Chyornenkaya
The Research Institute of Emergency Care n.a. N.V. Sklifosovsky
Russian Federation


N. V. Evdokimova
The Research Institute of Emergency Care n.a. N.V. Sklifosovsky
Russian Federation


References

1. Гостев В.В., Попенко Л.Н., Черненькая Т.В. [и др.] Оценка чувствительности MRSA к оксациллину, цефокситину, ванкомицину и даптомицину // Антибиотики и химиотерапия. - 2013. - Т. 58, № 9-10. - С. 13-20.

2. Козлова Н.С., Баранцевич Н.Е., Иванова Л.В. [и др.] Чувствительность к антибактериальным препаратам стафилококков, циркулирующих в многопрофильном стационаре // Проблемы медицинской микологии. - 2015. - Т. 17, № 4. - С. 58-62.

3. Сухорукова М.В, Склеенова Е.Ю., Иванчик Н.В. [и др.] Антибиотикорезистентность нозокомиальных штаммов Staphylococcus aureus в стационарах России: результаты многоцентрового эпидемиологического исследования МАРАФОН в 2011-2012 гг. // Клиническая микробиология и антимикробная химиотерапия. - 2014. - Т. 16, № 4. - С. 280-286.

4. Antibiotics resistance ‘as big a risk as terrorism’ [Электронный ресурс]. - Режим доступа: // http://www.bbc.com/news/health-21737844.

5. Antimicrobial resistance surveillance in Europe 2014 [Электронный ресурс]. - Режим доступа: http://ecdc.europa.eu/en/publications/Report%20Assets/AER-AMR-2014/S%20aureus/number-saureus-isolates-and-percentage-resistant-meticilin-2011-2014.png.

6. Coombs G.W., Daley D.A., Thin Lee Y. [et al.] Australian Group on Antimicrobial Resistance Australian Staphylococcus aureus Sepsis Outcome Programme annual report, 2014 // Commun. Dis. Intell. Q. Rep. - 2016. - Vol. 40, N. 2. - E244-254.

7. Dutton A.A., Elmes P.C. Vancomycin: report on treatment of patients with severe staphylococcal infections // Br. Med. J. - 1959 - Vol. 1. - P. 1144-5130.

8. European Committee on Antimicrobial Susceptibility Testing Breakpoint tables for interpretation of MICs and zone diameters Version 6.0, valid from 2016-01-01 [Электронный ресурс].- Режим доступа: http://www.eucast.org/fileadmin/src/media/PDFs/EUCAST_files/Breakpoint_tables/v_6.0_Breakpoint_table.pdf.

9. Harrison E.M., Ba X., Blane B. [et al.] PBP2a substitutions linked to ceftaroline resistance in MRSA isolates from the UK // J. Antimicrob. Chemother. - 2016. - Vol. 71, N. 1. - P. 268-269.

10. van Hal S.J., Lodise T.P., Paterson D.L. The clinical significance of vancomycin minimum inhibitory concentration in Staphylococcus aureus infections: a systematic review and meta-analysis // Clin. Infect. Dis. - 2012. - Vol. 54, N. 6. - P. 755-771.

11. Kelley W.L., Jousselin A., Barras Ch. [et al.] Missense Mutations in PBP2A Affecting ceftaroline susceptibility setected in epidemic hospital-acquired methicillin-resistant Staphylococcus aureus Clonotypes ST228 and ST247 in Western Switzerland archived since 1998 // Antimicrob. Agents Chemother. - 2015. - Vol. 59, N. 4. - P. 1922-1930.

12. World Health Organization. Antimicrobial resistance: global report on surveillance 2014 [Электронный ресурс] // Geneva, Switzerland: WHO, 2014. - Режим доступа: http://apps.who.int/iris/bitstream/10665/112642/1/9789241564748_eng.pdf?ua=1.


Review

For citations:


Chyornenkaya T.V., Evdokimova N.V. Antibiotic susceptibility of methicillin-resistant Staphylococcus spp., isolated from emergency hospital patients. Medical alphabet. 2017;1(7):32-35. (In Russ.)

Views: 315


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)