New aspects in rehabilitation of patients after interruption of undeveloped pregnancy

Abstract

The aim of the study was to assess the effectiveness of the combined effect of ultrasonic cavitation irrigation of the uterine cavity and peloid dyspepsia with hyposulfite muds on the change in the level of proinflammatory cytokines and the state of the microbiota of the genital tract in women after the interruption of the undeveloped pregnancy. The study included 65 women after the interruption of an undeveloped pregnancy in a period of up to 12 weeks. In the complex of therapy, the patients underwent cavitation ultrasonic irrigation of the uterine cavity with chlorhexidine solution 0.05 % in combination with the rectal administration of mud tampons and applications to the panties’ zone. Using the method of ultrasonic cavitation irrigation of the uterine cavity in combination with peloidotherapy in women after the interruption of the regressing pregnancy leads to a significant decrease in the level of the primary mediators of the inflammatory response of IL-8, IL-6 and TNF-alpha and normalization of the genital micro-biocenosis in comparison with the group in which Only standard antibiotic therapy was used.