Preview

Medical alphabet

Advanced search

New view on electroencephalographic pattern features of juvenile myoclonic epilepsy

Abstract

The lecture presents modern data on electroencephalographic pattern features of juvenile myoclonic epilepsy should include atypical morphology of complexes of spike-slow wave, amplitude asymmetry, focal discharges, focal onset seizures, focal displacement of the paroxysms, and the presence of generalized paroxysmal fast rhythms. Modern studies indicated the need for training of doctors of functional diagnostics and clinical neurophysiologists about the electroencephalographic characteristics of JME with the goal of timely disease diagnosis, exception the appointment of inadequate treatment.

About the Authors

N. A. Shnayder
National Medical Research Center for Psychiatry and Neurology of the Ministry of Health of Russian Federation
Russian Federation


O. S. Shilkina
Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Health of Russian Federation
Russian Federation


D. V. Dmitrenko
Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Health of Russian Federation
Russian Federation


References

1. Engel J.J. Report of the ILAE classification core group. Epilepsia. 2006; 47(9): 1558-1568.

2. Шилкина О.С., Шнайдер Н.А. Эпидемиология юношеской миоклонической эпилепсии. Неврология, нейропсихиатрия, психосоматика. 2017(1S): 26-31.

3. Карлов В.А., Фрейдкова Н.В. Юношеская миоклоническая эпилепсия. В книге: Эпилепсия у детей и взрослых женщин и мужчин. 2010; 244-8.

4. Panayiotopoulos C.P., Tahan R., Obeid T. Juvenile myoclonic epilepsy: factors of errors involved in the diagnosis and treatment Epilepsia. 1991; 32(5): 672-6.

5. Artyukhov I.P., Shilkina O.S., Shnayder N.A., Dmitrenko D.V. et al. Case report of management problem of juvenile myoclonic epilepsy. Case Reports in Clinical Medicine. 2016; (5): 217-224.

6. Serafini A., Rubboli G., Gigli G.L. Koutroumanidis M., et al. Neurophysiology of juvenile myoclonic epilepsy. Epilepsy Behav. 2013; 28(1): 30-9. doi: 10.1016/j.yebeh.2012.11.042.

7. Genton P., Puig X.S., Tunon A., Lahoz C., et al. Juvenile myoclonic epilepsy and related syndromes: clinical and neurophysiological aspects. In: Malafosse A., Genton P., Hirsch E., Marescaux C., et al. Idiopathic generalized epilepsies: clinical, experimental and genetic aspects. London, UK: John Libbey and Company Ltd; 1994: 253-65.

8. Santiago-Rodriguez E., Harmony T., Cardenas-Morales L., Hernandez A., et al. Analysis of background EEG activity in patients with juvenile myoclonic epilepsy. Seizure 2008; 17: 437-45.

9. Genton P., Gonzalez Sanchez M.S., Saltarelli A., Bureau M., et al. Misleading aspects of standard electro-encephalography in JME. Neurophysiol Clin 1995; 25: 283-90.

10. Betting L.E., Mory S.B., Lopes-Cendes I., Li M., et al. EEG features in idiopathic generalized epilepsy: clues to diagnosis. Epilepsia 2006; 47: 523-8.

11. Мухин К.Ю., Фрейдкова Н.В., Глухова А.Ю., Пылаева О.А., и др. Юношеская миоклоническая эпилепсия: фокус на эффективность терапии и частоту рецидивов по данным длительного катамнеза. Русский журнал детской неврологии 2015; 10(4): 7-16.

12. Panayiotopoulos C.P., Obeid T., Tahan A.R. Juvenile myoclonic epilepsy: a 5-year prospective study. Epilepsia 1994; 35: 285-96.

13. Baise-Zung C., Guilhoto L.M., Grossmann R.M. Juvenile myoclonic epilepsy: nonclassic electroencephalographical presentation in adult patients. Eur J Neurol 2006; 13: 171-5.

14. Aliberti V., Grünewald R.A., Panayiotopoulos C.P., Chroni E. Focal electroencephalographic abnormalities in juvenile myoclonic epilepsy. Epilepsia 1994; 35: 297-301.

15. Lancman M.E., Asconapé J.J., Penry J.K. Clinical and EEG asymmetries in juvenile myoclonic epilepsy. Epilepsia 1994; 35: 302-6.

16. Halasz P., Janszky J., Barcs G., Szucs A. Generalised paroxysmal fast activity (GPFA) is not always a sign of malignant epileptic encephalopathy. Seizure 2004; 13: 270-6.

17. Sagi V., et al. Generalized paroxysmal fast activity in EEG: An unrecognized finding in genetic generalized epilepsy. Epilepsy Behav.2017. http://dx.doi.org/10.1016/jyebeh.2017.08.019.

18. Murthy J.M., Rao C.M., Meena A.K. Clinical observations of juvenile myoclonic epilepsy in 131 patients: a study in South India. Seizure 1998; 7: 43-7.

19. Atakli D., Sozuer D., Atay T., Baybas S., Arpaci B. Misdiagnosis and treatment in juvenile myoclonic epilepsy. Seizure 1998; 7: 63-6.

20. Воронкова К.В., Холин А.А., Ахмедов Т.М., Мазальская О.А., Королева Н.Ю., Федин А.И. Фокальные черты идиопатических генерализованных эпилепсий. Результаты собственного исследования // Лечебное дело. 2012. № 2. С. 65-74]

21. Shahnaz А., Sher K., Sattar R.A. Clinical and EEG characteristics of Juvenile Myoclonic Epilepsy. Pak J Med Sci2014; 30(1): 12-15 doi: http://dx.doi.org/10.12669/pjms.301.4465

22. Seneviratne U., Hepworth G., Cook M., D’Souza W. Atypical EEG abnormalities in genetic generalized epilepsies. Clin Neurophysiol. 2016; 127(1): 214-220. doi: 10.1016/j.clinph.2015.05.031. Epub 2015 Jun 19.

23. Baise-Zung C., Guilhoto L.M., Grossmann R.M. Juvenile myoclonic epilepsy: nonclassic electroencephalographical presentation in adult patients. Eur J Neurol 2006; 13: 171-5.

24. MontalentiтE., Imperiale D., Rovera A., Bergamasco B., et al. Clinical features, EEG findings and diagnostic pitfalls in juvenilemyoclonic epilepsy: a series of 63 patients. J Neurol Sci 2001; 184: 65-70.

25. Lombroso C.T. Consistent EEG focalities detected in subjects with primary generalized epilepsies monitored for two decades. Epilepsia 1997; 38: 797-812.

26. Dhanuka A.K., Jain B.K., Singh D., Maheshwari D. Juvenile myoclonic epilepsy: a clinical and sleep EEG study. Seizure 2001; 10: 374-8.

27. Jayalakshmi S.S., Srinivasa Rao B., Sailaja S. Focal clinical and electroencephalographic features in patients with juvenile myoclonic epilepsy. Acta Neurol Scand 2010; 122: 115-23.

28. Japaridze G., Kasradze S., Lomidze G., Zhizhiashvili L., et al. Focal EEG features and therapeutic response in patients with juvenile absence and myoclonic epilepsy. Clin Neurophysiol. 2016; 127(2): 1182-7. doi: 10.1016/j.clinph.2015.11.048.

29. Esmail E.H., Nawito A.M., Labib D.M., Basheer M.A. Focal interictal epileptiform discharges in idiopathic generalized epilepsy. Neurol Sci. 2016; 37(7): 1071-7. doi: 10.1007/s10072-016-2538-5.

30. Kasteleijn-Nolst Trenité D.G., de Weerd A., Beniczky S. Chronodependency and provocative factors in juvenile myoclonic epilepsy. Epilepsy Behav. 2013; 28(1): 25-9. doi: 10.1016/j.yebeh.2012.11.045.

31. Appleton, R., Beirne, M., Acomb, B. Photosensitivity in juvenile myoclonic epilepsy. Seizure 2000; 9: 108-111.

32. Beniczky S., Guaranha M.S., Conradsen I., Singh M.B. et al. Modulation of epileptiform EEG discharges in juvenile myoclonic epilepsy: an investigation of reflex epileptic traits. Epilepsia. 2012 May; 53(5): 832-9. doi: 10.1111/j.1528-1167.2012.03454.x.

33. Genton P., Gelisse P., Thomas P. Juvenile myoclonic epilepsy today: current definition and limits. In: Schmitz B., Sander T., editors. Juvenile myoclonic epilepsy: the Janz syndrome. Petersfield and Philadelphia: Wrightson Medical Publishing. 2000: 11-32.

34. Карлов В.А. Фотосенситивность, эпилепсия, затылочная и лобная кора. Эпилепсия и пароксизмальные состояния. 2014; 6(4): 31-36.

35. Touchon J. Effect of awakening on epileptic activity in primary generalized myoclonic epilepsy. In: Sterman M.B., Shouse M.N., Passouant P., editors. Sleep and epilepsy New York: Academic Press; 1982: 239-47.

36. Billiard M. Epilepsiesandthesleep-wakecycle. In: Sterman M.B., Shouse M.N., Passouant P., editors. Sleepandepilepsy. NewYork: AcademicPress. 1982: 269-89.

37. SalasPuig J., Tunon J.A., Mateos V., Guisasola L.M., et al. Janz’s juvenile myoclonic epilepsy: a little known frequent syndrome. Med Clin 1994; 103: 684-9.

38. Janz D., Christian W. Impulsiv - petit mal. Deutsche Zeitschrift für Nervenheilkunde 1957;.176:.346-86. (English translation by Genton P. In: Malafosse A., Genton P., Hirsch E., Marescaux C., Broglin D., Bernasconi M., editors. Idiopathic generalized epilepsies. London: John Libbey; 1994:229-51.

39. Panayiotopoulos C.P. A clinical guide to epileptic syndromes and their treatment, revised 2nd ed. London: Springer Healthcare Ltd. 2010.

40. Morison R.S., Dempsey E.W. A study of thalamo-cortical relations. Am J Physiol 1941; 135: 281-292.

41. Meeren H., van Luijtelaar G., Lopes da Silva F., Coenen A. Evolving concepts on the pathophysiology of absence seizures: the cortical focus theory. Arch Neurol 2005; 62: 371-376.

42. Penfield W.G., Jasper H.H. Epilepsy and functional anatomy of the human brain. Little Brown & Co, Boston, MA. 1954.

43. Buzsaki G. The thalamic clock: emergent network properties. Neuroscience 1991; 41: 351-364.

44. Gloor P. Generalized cortico-reticular epilepsies: some considerations on the pathophysiology of generalized bilaterally synchronous spike and wave discharge. Epilepsia 1968; 9:.249-263.

45. Gloor P. Generalized epilepsy with bilateral synchronous spike and wave discharge. New findings concerning its physiological mechanisms. Electroencephalogr Clin Neurophysiol Suppl 1978; 34: 245-249.

46. Leresche N., Lambert R.C., Errington A.C., Crunelli V. From sleep spindles of natural sleep to spike and wave discharges of typical absence seizures: is the hypothesis still valid? Pflugers Arch. 2011. doi: 10.1007/s00424-011-1009-3.

47. Laws E., Niedermeyer E., Walker A.E. Depth E.E.G. findings in epileptics with generalzed spike-wave complexes. Electroencephalogr Clin Neurophysiol 1970; 28: 94-95.

48. Moeller F., Maneshi M., Pittau F., Gholipour T., et al. Functional connectivity in patients with idiopathic generalized epilepsy. Epilepsia 2011; 52: 515-522.

49. Clemens B., Puskds S., Besenyei M., Spisdk T., Opposite G., Hollôdy K., Fogarasi A., Fekete I., Emri M. Neurophysiology of juvenile myoclonic epilepsy: EEG-based network and graph analysis of the interictal and immediate preictal states. Epilepsy Res. 2013; 106(3): 357-69. doi: 10.1016/j.eplepsyres.2013.06.017. Epub 2013 Jul22.

50. Vollmar C., O’Muircheartaigh J., Barker G.J., et al. Motor system hyperconnectiviiy in juvenile myoclonic epilepsy: a cognitive functional magnetic resonance imaging study. Brain 2011; 134: 1710-1719.

51. Matsuoka H., Takahashi T., Sasaki M., et al. Neuropsychological EEG activation in patients with epilepsy. Brain 2000; 123: 318-330.

52. O’Muircheartaigh J., Vollmar C., Barker G.J., et al. Focal structural changes and cognitive dysfunction in juvenile myoclonic epilepsy. Neurology 2011; 76: 34-40.

53. Vollmar C., O’Muircheartaigh J., Symms M.R., Barker G.J., et al. Altered microstructural connectivity in juvenile myoclonic epilepsy: the missing link. Neurology. 2012; 78(20): 1555-9. doi: 10.1212/WNL.0b013e3182563b44.

54. Rodin E., Ancheta O. (1987) Cerebral electrical fields during petit фmal absences. Electroencephalogr Clin Neurophysiol 66: 457-466.

55. Holmes M.D., Brown M., Tucker D.M. Are "generalized" seizures truly generalized? Evidence of localized mesial frontal and frontopolar discharges in absence. Epilepsia 2004; 45: 1568-1579.

56. Карлов В.А., Гнездицкий В.В., Баярмаа Дойлов. Транскраниальная магнитная стимуляция при эпилепсии: показания и противопоказания. Международная конференция «Эпилепсия - диагностика, лечение» М. 2005; 162-167.

57. Bartolini E., Pesaresi I., Fabbri S., Cecchi P., et al. Abnormal response to photic stimulation in juvenile myoclonic epilepsy: an EEG-fM-RI study. Epilepsia. 2014; 55(7): 1038-47. doi: 10.1111/epi.12634.

58. Blumenfeld H. Cellular and network mechanisms of spike-wave seizures. Epilepsia 2005; 46(9): 21-33.

59. Altindag E 1, Baslo B., Baykan B., Bebek N., et al. Reduced axon number in juvenile myoclonic epilepsy demonstrated by motor unit number estimation analysis. Clin EEG Neurosci. 2007; 38(3): 127-31.

60. Шнайдер Н.А., Шилкина О.С., Петров К.В., Черных И.А., и др. Клинико-генетическая гетерогенность юношеской миоклонической эпилепсии. Эпилепсия и пароксизмальные состояния. 2016; 2: 20-36.


Review

For citations:


Shnayder N.A., Shilkina O.S., Dmitrenko D.V. New view on electroencephalographic pattern features of juvenile myoclonic epilepsy. Medical alphabet. 2018;2(23):6-12. (In Russ.)

Views: 298


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)